Sawako Goto
Overview
Explore the profile of Sawako Goto including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
230
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sofuku R, Miyazaki S, Hosojima M, Goto S, Takemoto K, Kabasawa H, et al.
J Immunol Methods
. 2024 Oct;
534:113763.
PMID: 39374646
Megalin, a type I transmembrane protein, serves as a multi-ligand endocytic receptor in the apical membrane of proximal tubules. Its ectodomain and full-length forms are excreted into human urine, with...
2.
Goto S, Tsutsumi A, Lee Y, Hosojima M, Kabasawa H, Komochi K, et al.
Proc Natl Acad Sci U S A
. 2024 May;
121(22):e2318859121.
PMID: 38771880
Megalin (low-density lipoprotein receptor-related protein 2) is a giant glycoprotein of about 600 kDa, mediating the endocytosis of more than 60 ligands, including those of proteins, peptides, and drug compounds...
3.
Goto S, Hosojima M, Kabasawa H, Arai K, Takemoto K, Aoki H, et al.
J Pathol
. 2024 May;
263(3):315-327.
PMID: 38721910
Hemolysis-induced acute kidney injury (AKI) is attributed to heme-mediated proximal tubule epithelial cell (PTEC) injury and tubular cast formation due to intratubular protein condensation. Megalin is a multiligand endocytic receptor...
4.
Bokhove M, Kawamura T, Okumura H, Goto S, Kawano Y, Werner S, et al.
J Biol Chem
. 2024 Apr;
300(5):107289.
PMID: 38636663
Vitamin B (cobalamin or Cbl) functions as a cofactor in two important enzymatic processes in human cells, and life is not sustainable without it. B is obtained from food and...
5.
Tsuchida M, Goto S, Watanabe H, Goto S, Yamaguchi H, Narita I
Mol Genet Genomic Med
. 2023 Oct;
12(1):e2288.
PMID: 37795781
Introduction: Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy. Personal genome analyses have revealed numerous aHUS-causing variants, mainly complement-related genes. However, not all aHUS-causing variants have...
6.
Goto S, Yoshida Y, Hosojima M, Kuwahara S, Kabasawa H, Aoki H, et al.
J Hypertens
. 2023 Sep;
41(11):1831-1843.
PMID: 37682076
Background: Kidney angiotensin (Ang) II is produced mainly from liver-derived, glomerular-filtered angiotensinogen (AGT). Podocyte injury has been reported to increase the kidney Ang II content and induce Na + retention...
7.
Goto S, Hosojima M, Kabasawa H, Saito A
Int J Biochem Cell Biol
. 2023 Mar;
157:106393.
PMID: 36863658
The large (∼600 kDa) endocytosis receptor megalin/low-density lipoprotein receptor-related protein 2 is highly expressed at the apical membrane of proximal tubular epithelial cells (PTECs). Megalin plays an important role in...
8.
Iida T, Hosojima M, Kabasawa H, Yamamoto-Kabasawa K, Goto S, Tanaka T, et al.
J Diabetes Complications
. 2022 Oct;
36(11):108312.
PMID: 36228564
Aims: Megalin, a proximal tubular endocytosis receptor, is excreted in urine in two forms: ectodomain (A-megalin) and full-length (C-megalin). We explored whether urinary megalin levels can be used as independent...
9.
Kawakami R, Matsui M, Konno A, Kaneko R, Shrestha S, Shrestha S, et al.
J Pathol
. 2021 Aug;
255(4):362-373.
PMID: 34370295
Urinary fatty acid binding protein 1 (FABP1, also known as liver-type FABP) has been implicated as a biomarker of acute kidney injury (AKI) in humans. However, the precise biological mechanisms...
10.
Arita M, Watanabe S, Aoki N, Kuwahara S, Suzuki R, Goto S, et al.
Sci Rep
. 2021 Jan;
11(1):750.
PMID: 33437029
Cisplatin, one of the most active anticancer agents, is widely used in standard chemotherapy for various cancers. Cisplatin is more poorly tolerated than other chemotherapeutic drugs, and the main dose-limiting...