Saverio Alberti
Overview
Explore the profile of Saverio Alberti including associated specialties, affiliations and a list of published articles.
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67
Citations
1501
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Recent Articles
1.
Trerotola M, Relli V, Tripaldi R, Simeone P, Guerra E, Sacchetti A, et al.
Mol Biol Cell
. 2025 Jan;
36(3):ar38.
PMID: 39785844
The transmembrane glycoproteins Trop-1/EpCAM and Trop-2 independently trigger Ca and kinase signals for cell growth and tumor progression. Our findings indicated that Trop-1 and Trop-2 tightly colocalize at macroscopic, ruffle-like...
2.
Verhagen M, Xu T, Stabile R, Joosten R, Tucci F, van Royen M, et al.
iScience
. 2024 Sep;
27(9):110658.
PMID: 39246444
Intra-tumor heterogeneity, i.e., the presence of diverse cell types and subpopulations within tumors, presents a significant obstacle in cancer treatment due to its negative consequences for resistance to therapy and...
3.
Giansante V, Angelo L, Calabrese C, De Sanctis P, Regi P, Martelli F, et al.
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38673897
Pancreatic cancer, most frequently as ductal adenocarcinoma (PDAC), is the third leading cause of cancer death. Clear-cell primary adenocarcinoma of the pancreas (CCCP) is a rare, aggressive, still poorly characterized...
4.
Guerra E, Trerotola M, Relli V, Lattanzio R, Boujnah K, Travali N, et al.
Front Genet
. 2024 Jan;
14:1297367.
PMID: 38250577
A phylogenetic conservation analysis of Trop-2 across vertebrate species showed a high degree of sequence conservation, permitting to explore multiple models as pre-clinical benchmarks. Sequence divergence and incomplete conservation of...
5.
Grassadonia A, Carletti E, De Luca A, Vici P, Di Lisa F, Filomeno L, et al.
J Cancer
. 2023 Oct;
14(15):2751-2758.
PMID: 37781086
Sex might influence prognosis in patients affected by colorectal cancer. We retrospectively studied a cohort of patients affected by metastatic colon cancer (mCC) stratified by sex and primary tumor location....
6.
Giansante V, Stati G, Sancilio S, Guerra E, Alberti S, Di Pietro R
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628814
Pancreatic cancer (PC) is the seventh leading cause of cancer-related death. PC incidence has continued to increase by about 1% each year in both men and women. Although the 5-year...
7.
Guerra E, Trerotola M, Alberti S
J Clin Oncol
. 2023 Aug;
41(29):4688-4692.
PMID: 37549340
No abstract available.
8.
Guerra E, Trerotola M, Relli V, Lattanzio R, Ceci M, Boujnah K, et al.
Cancers (Basel)
. 2023 Jul;
15(14).
PMID: 37509383
Trop-2 proteolytic processing in cancer cells exposes epitopes that were specifically targeted by the 2G10 antibody. We sought additional recognition of Trop-2 within difficult-to-reach, densely packed tumor sites. Trop-2 deletion...
9.
Guerra E, Di Pietro R, Stati G, Alberti S
Front Oncol
. 2023 Jul;
13:1151090.
PMID: 37456256
The advent of high throughput DNA sequencing is providing massive amounts of tumor-associated mutation data. Implicit in these analyses is the assumption that, by acquiring a series of hallmark changes,...
10.
Guerra E, Trerotola M, Relli V, Lattanzio R, Tripaldi R, Ceci M, et al.
Mol Cancer Ther
. 2023 Mar;
22(6):790-804.
PMID: 36921314
Next-generation Trop-2-targeted therapy against advanced cancers is hampered by expression of Trop-2 in normal tissues. We discovered that Trop-2 undergoes proteolytic activation by ADAM10 in cancer cells, leading to the...