Saurav Brahmachari
Overview
Explore the profile of Saurav Brahmachari including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
29
Citations
2379
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mao X, Gu H, Kim D, Kimura Y, Wang N, Xu E, et al.
Nat Commun
. 2024 Jul;
15(1):6413.
PMID: 39080298
No abstract available.
2.
Mao X, Gu H, Kim D, Kimura Y, Wang N, Xu E, et al.
Nat Commun
. 2024 May;
15(1):4663.
PMID: 38821932
Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β precursor-like protein 1 (Aplp1) interacts with Lag3 that...
3.
Khan M, Yin X, Kang S, Mitra J, Wang H, Ryu T, et al.
Sci Transl Med
. 2023 Nov;
15(724):eadd0499.
PMID: 38019930
Pathologic α-synuclein plays an important role in the pathogenesis of α-synucleinopathies such as Parkinson's disease (PD). Disruption of proteostasis is thought to be central to pathologic α-synuclein toxicity; however, the...
4.
Karuppagounder S, Wang H, Kelly T, Rush R, Nguyen R, Bisen S, et al.
Sci Transl Med
. 2023 Jan;
15(679):eabp9352.
PMID: 36652533
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease of the central nervous system, with an estimated 5,000,000 cases worldwide. PD pathology is characterized by the accumulation of misfolded...
5.
Panicker N, Kam T, Wang H, Neifert S, Chou S, Kumar M, et al.
Neuron
. 2022 Jun;
110(15):2422-2437.e9.
PMID: 35654037
Parkinson's disease (PD) is mediated, in part, by intraneuronal accumulation of α-synuclein aggregates andsubsequent death of dopamine (DA) neurons in the substantia nigra pars compacta (SNpc). Microglial hyperactivation of the...
6.
Hinkle J, Patel J, Panicker N, Karuppagounder S, Biswas D, Belingon B, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(15):e2118819119.
PMID: 35394877
In idiopathic Parkinson’s disease (PD), pathologic αSyn aggregates drive oxidative and nitrative stress that may cause genomic and mitochondrial DNA damage. These events are associated with activation of the cyclic...
7.
Ma S, Seo B, Kim D, Xiong Y, Kwon S, Brahmachari S, et al.
J Proteome Res
. 2021 Jun;
20(7):3428-3443.
PMID: 34061533
Parkinson's disease (PD) is the second most common neurodegenerative disorder that results in motor dysfunction and, eventually, cognitive impairment. α-Synuclein protein is known as a central protein to the pathophysiology...
8.
Gu H, Yang X, Mao X, Xu E, Qi C, Wang H, et al.
Front Cell Neurosci
. 2021 Mar;
15:656426.
PMID: 33776654
Aggregation of misfolded α-synuclein (α-syn) is the major component of Lewy bodies and neurites in Parkinson's disease (PD) and related α-synucleinopathies. Some α-syn mutations (e.g., A53T) in familial PD recapitulate...
9.
Kumar M, Acevedo-Cintron J, Jhaldiyal A, Wang H, Andrabi S, Eacker S, et al.
Stem Cell Reports
. 2020 Aug;
15(3):629-645.
PMID: 32795422
Mutations and loss of activity in PARKIN, an E3 ubiquitin ligase, play a role in the pathogenesis of Parkinson's disease (PD). PARKIN regulates many aspects of mitochondrial quality control including...
10.
Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder S, Ge P, et al.
Brain
. 2019 Jun;
142(8):2380-2401.
PMID: 31237944
α-Synuclein misfolding and aggregation plays a major role in the pathogenesis of Parkinson's disease. Although loss of function mutations in the ubiquitin ligase, parkin, cause autosomal recessive Parkinson's disease, there...