Sasha Z Prisco
Overview
Explore the profile of Sasha Z Prisco including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
330
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Recent Articles
1.
Precision Medicine for Pulmonary Vascular Disease: The Future Is Now (2023 Grover Conference Series)
Forbes L, Bauer N, Bhadra A, Bogaard H, Choudhary G, Goss K, et al.
Pulm Circ
. 2025 Jan;
15(1):e70027.
PMID: 39749110
Pulmonary vascular disease is not a single condition; rather it can accompany a variety of pathologies that impact the pulmonary vasculature. Applying precision medicine strategies to better phenotype, diagnose, monitor,...
2.
Kazmirczak F, Vogel N, Prisco S, Patterson M, Annis J, Moon R, et al.
Circ Res
. 2024 Oct;
135(11):1067-1083.
PMID: 39421926
Background: Mitochondrial dysfunction, characterized by impaired lipid metabolism and heightened reactive oxygen species generation, results in lipid peroxidation and ferroptosis. Ferroptosis is an inflammatory mode of cell death that promotes...
3.
Prisco S, Blake M, Kazmirczak F, Moon R, Vogel N, Moutsoglou D, et al.
bioRxiv
. 2024 Sep;
PMID: 39229028
Emerging data demonstrate systemic and local inflammation regulate right ventricular (RV) adaption in preclinical and human pulmonary arterial hypertension (PAH). Pathological RV inflammation is targetable as antagonism of glycoprotein-130 (GP130)...
4.
Prisco S, Hartweck L, Kazmirczak F, Mendelson J, Deng S, Blake M, et al.
Circulation
. 2024 Aug;
150(8):657-660.
PMID: 39159221
No abstract available.
5.
Kazmirczak F, Thenappan T, Prins K, Prisco S
Pulm Circ
. 2023 Sep;
13(3):e12288.
PMID: 37719340
Group 3 pulmonary hypertension (PH) patients have disproportionate right ventricular dysfunction (RVD) compared to pulmonary arterial hypertension. We evaluated how sex and PH etiology modulated RVD. Strain echocardiography showed no...
6.
Kazmirczak F, Prisco S, Knoper R, Huddleston S, Raveendran G, Pritzker M, et al.
J Invasive Cardiol
. 2023 Jul;
35(6):E312-E320.
PMID: 37410748
Introduction: Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive and debilitating disorder that results from incomplete resolution of vascular obstructions resulting in pulmonary hypertension. Surgical pulmonary thromboendarterectomy (PTE) is the...
7.
Kazmirczak F, Hartweck L, Vogel N, Mendelson J, Park A, Raveendran R, et al.
JACC Basic Transl Sci
. 2023 Apr;
8(3):239-254.
PMID: 37034280
Intermittent fasting (IF) extends life span via pleotropic mechanisms, but one important molecular mediator is adenosine monophosphate-activated protein kinase (AMPK). AMPK enhances lipid metabolism and modulates microtubule dynamics. Dysregulation of...
8.
Prisco S, Hartweck L, Kazmirczak F, Mendelson J, Deng S, Lahiri S, et al.
bioRxiv
. 2023 Feb;
PMID: 36798293
Right ventricular dysfunction (RVD) is a risk factor for mortality in multiple cardiovascular diseases, but approaches to combat RVD are lacking. Therapies used for left heart failure are largely ineffective...
9.
Kazmirczak F, Vogel N, Prisco S, Patterson M, Annis J, Moon R, et al.
bioRxiv
. 2023 Jan;
PMID: 36712076
Background: Mitochondrial dysfunction, characterized by impaired lipid metabolism and heightened reactive oxygen species (ROS) generation, results in lipid peroxidation and ferroptosis. Ferroptosis is an inflammatory mode of cell death that...
10.
Moutsoglou D, Tatah J, Prisco S, Prins K, Staley C, Lopez S, et al.
Am J Respir Crit Care Med
. 2022 Nov;
207(6):740-756.
PMID: 36343281
Inflammation drives pulmonary arterial hypertension (PAH). Gut dysbiosis causes immune dysregulation and systemic inflammation by altering circulating microbial metabolites; however, little is known about gut dysbiosis and microbial metabolites in...