Saraswathi Naravula
Overview
Explore the profile of Saraswathi Naravula including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
4
Citations
250
Followers
0
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Top 10 Co-Authors
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Recent Articles
1.
Chernyak N, Bhagwat B, Naravula S, Chen Y, Solban N, Zhang F, et al.
J Med Chem
. 2024 Sep;
67(18):16222-16234.
PMID: 39235949
Toll-like receptor (TLR) activation converts immunologically inactive tumors into immunologically active tumors by activating tumor residing antigen-presenting cells and recruitment of cytotoxic T lymphocytes. Targeted immune agonists (TIAs) are antibody...
2.
Patel A, Willingham A, Cheng A, Tomazela D, Bowman E, Kofman E, et al.
J Med Chem
. 2024 Aug;
67(17):15756-15779.
PMID: 39172064
Toll-like receptors 7 and 8 are involved in modulating the adaptive and innate immune responses, and their activation has shown promise as a therapeutic strategy in the field of immuno-oncology....
3.
Sukumar S, Wilson D, Yu Y, Wong J, Naravula S, Ermakov G, et al.
Cancer Res
. 2017 Jun;
77(16):4378-4388.
PMID: 28611044
GITR is a T-cell costimulatory receptor that enhances cellular and humoral immunity. The agonist anti-mouse GITR antibody DTA-1 has demonstrated efficacy in murine models of cancer primarily by attenuation of...
4.
Mumm J, Emmerich J, Zhang X, Chan I, Wu L, Mauze S, et al.
Cancer Cell
. 2011 Dec;
20(6):781-96.
PMID: 22172723
Tumor immune surveillance and cancer immunotherapies are thought to depend on the intratumoral infiltration of activated CD8(+) T cells. Intratumoral CD8(+) T cells are rare and lack activity. IL-10 is...