Sarah Legrain
Overview
Explore the profile of Sarah Legrain including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
27
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Recent Articles
1.
Legrain S, Su D, Gaignage M, Breukel C, Claassens J, Brouwers C, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445732
Infection with viruses, such as the lactate dehydrogenase-elevating virus (LDV), is known to trigger the onset of autoimmune anemia through the enhancement of the phagocytosis of autoantibody-opsonized erythrocytes by activated...
2.
Marro B, Legrain S, Ware B, Oldstone M
JCI Insight
. 2019 Jan;
4(2).
PMID: 30674713
Here, we report a pathogenic role for type I IFN (IFN-I) signaling in macrophages, and not β cells in the islets, for the development of type 1 diabetes (T1D). Following...
3.
Legrain S, Su D, Breukel C, Detalle L, Claassens J, van der Kaa J, et al.
J Immunol
. 2015 Sep;
195(9):4171-5.
PMID: 26385523
IgM anti-mouse platelet autoantibodies cause thrombocytopenia by mediating uptake of opsonized thrombocytes, whereas IgM anti-erythrocyte autoantibodies induce anemia through a phagocytosis-independent cell destruction. In this article, we show that infection...
4.
Su D, Musaji A, Legrain S, Detalle L, van der Kaa J, Verbeek J, et al.
J Virol
. 2012 Aug;
86(22):12414-6.
PMID: 22933286
Previously we demonstrated that antibody-mediated thrombocytopenia is strongly enhanced by lactate dehydrogenase-elevating virus (LDV) infection. Here we report that mice infected with LDV develop a moderate thrombocytopenia, even in the...