Sarah J Martins da Silva
Overview
Explore the profile of Sarah J Martins da Silva including associated specialties, affiliations and a list of published articles.
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15
Citations
195
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0
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Recent Articles
1.
Prajapati P, Kane S, McBrinn R, Dean M, Martins da Silva S, Brown S
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232560
Progesterone and prostaglandin E1 are postulated to trigger the human sperm acrosome reaction (AR). However, their reported efficacy is very variable which likely, in part, reflects the plethora of experimental...
2.
Attia A, Nicholson C, Martins da Silva S
Semin Reprod Med
. 2022 Mar;
39(5-06):e5-e11.
PMID: 35272388
Artificial oocyte activation, most commonly using calcium ionophore, is a treatment add-on utilized to avoid recurrence of abnormally low or total failed fertilization following in vitro fertilization/intracytoplasmic sperm injection. It...
3.
Aggarwal B, Evans A, Ryan H, Martins da Silva S
Reprod Fertil
. 2022 Feb;
2(1):L1-L3.
PMID: 35128437
In IVF, eggs and sperm are added together for fertilisation to occur whereas ICSI involves injecting a single sperm into each egg. ICSI is very effective where sperm count or...
4.
Walters J, Anderson A, Martins da Silva S, Aitken R, De Iuliis G, Sutherland J, et al.
Antioxidants (Basel)
. 2021 Jan;
10(1).
PMID: 33396527
A prevalent cause of sperm dysfunction in male infertility patients is the overproduction of reactive oxygen species, an attendant increase in lipid peroxidation and the production of cytotoxic reactive carbonyl...
5.
Martins da Silva S, Campo-Engelstein L
Reprod Biomed Online
. 2020 Dec;
42(2):287-290.
PMID: 33279418
Fertility services were significantly curtailed or suspended as an initial response to the coronavirus (COVID-19) pandemic earlier this year, following guidance from European Society for Human Reproduction and Embryology (ESHRE)...
6.
Martins da Silva S
Reprod Biomed Online
. 2019 Nov;
39(6):879-883.
PMID: 31727498
Oxidative stress is detrimental to spermatozoa and is acknowledged to be a common pathology in infertile men. Antioxidant supplements, therefore, represent a logical therapeutic approach, although the recent Cochrane review...
7.
Brown S, Publicover S, Barratt C, Martins da Silva S
Hum Reprod Update
. 2019 Oct;
25(6):758-776.
PMID: 31665287
Background: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of...
8.
McBrinn R, Fraser J, Hope A, Gray D, Barratt C, Martins da Silva S, et al.
Br J Pharmacol
. 2019 Aug;
176(23):4521-4536.
PMID: 31368510
Background And Purpose: Asthenozoospermia is a leading cause of male infertility, but development of pharmacological agents to improve sperm motility is hindered by the lack of effective screening platforms and...
9.
Martins da Silva S, Brown S, Sutton K, King L, Ruso H, Gray D, et al.
Hum Reprod
. 2017 Mar;
32(5):974-984.
PMID: 28333338
Study Question: Can pharma drug discovery approaches be utilized to transform investigation into novel therapeutics for male infertility? Summary Answer: High-throughput screening (HTS) is a viable approach to much-needed drug...
10.
Yeste M, Jones C, Amdani S, Yelumalai S, Mounce G, Martins da Silva S, et al.
Sci Rep
. 2016 Jun;
6:27543.
PMID: 27270687
Socio-economic factors have led to an increasing trend for couples to delay parenthood. However, advancing age exerts detrimental effects upon gametes which can have serious consequences upon embryo viability. While...