Sarah E Rowe
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Explore the profile of Sarah E Rowe including associated specialties, affiliations and a list of published articles.
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32
Citations
1506
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Recent Articles
1.
Shook J, Genito C, Darwitz B, Tyson K, Velez A, Bridwell S, et al.
Sci Adv
. 2025 Feb;
11(7):eads1591.
PMID: 39937900
Individuals with diabetes mellitus frequently develop severe skin and soft tissue infections (SSTIs) that are recalcitrant to antibiotic treatment. We examined how diabetes affects the emergence of antibiotic resistance in...
2.
Tabashsum Z, Angeles-Solano M, Sidders A, Parsons J, Rowe S
Microbiol Spectr
. 2024 Dec;
13(1):e0199624.
PMID: 39656010
The rise in antibiotic resistance limits the availability of antibiotics to treat bacterial infections. Despite this, antibiotic development pipelines remain sparse which makes using adjuvants to reverse antibiotic resistance a...
3.
Lu K, Yang X, Eldridge M, Wagner N, Hardy B, Axtman M, et al.
bioRxiv
. 2024 Nov;
PMID: 39554024
There are two major problems in the field of antimicrobial chemotherapy-antibiotic resistance and antibiotic tolerance. In the case of antibiotic tolerance, antibiotics fail to kill the bacteria as their phenotypic...
4.
Liu J, Van Treeck K, Marston W, Papadopoulou V, Rowe S
Chembiochem
. 2024 Jun;
25(20):e202400181.
PMID: 38924307
Bacterial biofilms are a significant concern in various medical contexts due to their resilience to our immune system as well as antibiotic therapy. Biofilms often require surgical removal and frequently...
5.
Parsons J, Sidders A, Velez A, Hanson B, Angeles-Solano M, Ruffin F, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(3):e2314514121.
PMID: 38190524
Gram-negative bacterial bloodstream infections (GNB-BSI) are common and frequently lethal. Despite appropriate antibiotic treatment, relapse of GNB-BSI with the same bacterial strain is common and associated with poor clinical outcomes...
6.
Beam J, Wagner N, Lu K, Parsons J, Fowler Jr V, Rowe S, et al.
iScience
. 2023 Oct;
26(10):107942.
PMID: 37790275
is a leading human pathogen that frequently causes relapsing infections. The failure of antibiotics to eradicate infection contributes to infection relapse. Host-pathogen interactions have a substantial impact on antibiotic susceptibility...
7.
Parker D, Koch J, Gish C, Brothers K, Li W, Gilbertie J, et al.
Life (Basel)
. 2023 Jun;
13(6).
PMID: 37374013
Hydrogen peroxide, povidone-iodine, and chlorhexidine are antiseptics that are commonly added to irrigants to either prevent or treat infection. There are little clinical data available that demonstrate efficacy of adding...
8.
Papadopoulou V, Sidders A, Lu K, Velez A, Durham P, Bui D, et al.
Cell Chem Biol
. 2023 May;
30(5):513-526.e5.
PMID: 37148883
Chronic wounds frequently become infected with bacterial biofilms which respond poorly to antibiotic therapy. Aminoglycoside antibiotics are ineffective at treating deep-seated wound infections due to poor drug penetration, poor drug...
9.
Sidders A, Kedziora K, Arts M, Daniel J, De Benedetti S, Beam J, et al.
Elife
. 2023 Mar;
12.
PMID: 36876902
Antibiotic tolerance and antibiotic resistance are the two major obstacles to the efficient and reliable treatment of bacterial infections. Identifying antibiotic adjuvants that sensitize resistant and tolerant bacteria to antibiotic...
10.
Beam J, Maiocchi S, Cartaya A, Rowe S, Bahnson E, Conlon B
Microbiol Spectr
. 2022 May;
10(3):e0085822.
PMID: 35575507
Interactions between Staphylococcus aureus and the host immune system can have significant impacts on antibiotic efficacy, suggesting that targeting and modulating the immune response to S. aureus infection may improve...