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Sarah Duponchel

Explore the profile of Sarah Duponchel including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 145
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Recent Articles
1.
Molle J, Duponchel S, Rieusset J, Ovize M, Ivanov A, Zoulim F, et al.
Viruses . 2025 Jan; 17(1. PMID: 39861799
Cyclophilin (Cyp) inhibitors are of clinical interest in respect to their antiviral activities in the context of many viral infections including chronic hepatitis B and C. Cyps are a group...
2.
Zakirova N, Khomich O, Smirnova O, Molle J, Duponchel S, Yanvarev D, et al.
Cells . 2024 Jun; 13(12. PMID: 38920664
Hepatitis C virus (HCV) is an oncogenic virus that causes chronic liver disease in more than 80% of patients. During the last decade, efficient direct-acting antivirals were introduced into clinical...
3.
Duponchel S, Monnier L, Molle J, Bendridi N, Alam M, Gaballah A, et al.
JHEP Rep . 2023 Jan; 5(3):100647. PMID: 36718430
Background & Aims: Chronic HCV infection causes cellular stress, fibrosis and predisposes to hepatocarcinogenesis. Mitochondria play key roles in orchestrating stress responses by regulating bioenergetics, inflammation and apoptosis. To better...
4.
Hackl T, Duponchel S, Barenhoff K, Weinmann A, Fischer M
Elife . 2021 Oct; 10. PMID: 34698016
Virophages can parasitize giant DNA viruses and may provide adaptive anti-giant virus defense in unicellular eukaryotes. Under laboratory conditions, the virophage mavirus integrates into the nuclear genome of the marine...
5.
Hackl T, Martin R, Barenhoff K, Duponchel S, Heider D, Fischer M
Sci Data . 2020 Jan; 7(1):29. PMID: 31964893
The heterotrophic stramenopile Cafeteria roenbergensis is a globally distributed marine bacterivorous protist. This unicellular flagellate is host to the giant DNA virus CroV and the virophage mavirus. We sequenced the...
6.
Duponchel S, Fischer M
PLoS Pathog . 2019 Mar; 15(3):e1007592. PMID: 30897185
No abstract available.
7.
Levy P, Duponchel S, Eischeid H, Molle J, Michelet M, Diserens G, et al.
Hepatology . 2016 Nov; 65(3):789-803. PMID: 27863447
Conclusion: Our data suggest that HCV establishes glutamine dependence, which is required for viral replication, and, importantly, that glutamine addiction is a hallmark of tumor cells. While HCV induces glutaminolysis...
8.
Brault C, Levy P, Duponchel S, Michelet M, Salle A, Pecheur E, et al.
Gut . 2014 Dec; 65(1):144-54. PMID: 25516417
Objective: Inflammation and oxidative stress drive disease progression in chronic hepatitis C (CHC) towards hepatocellular carcinoma. HCV is known to increase intracellular levels of reactive oxygen species (ROS), but how...
9.
Duponchel S, Troupin C, Vu L, Schnuriger A, Trugnan G, Garbarg-Chenon A
J Gen Virol . 2014 Jun; 95(Pt 9):2089-2098. PMID: 24906979
Group A rotaviruses, members of the family Reoviridae, are a major cause of infantile acute gastroenteritis. The rotavirus genome consists of 11 dsRNA segments. In some cases, an RNA segment...
10.
Troupin C, Schnuriger A, Duponchel S, Deback C, Schnepf N, Dehee A, et al.
PLoS One . 2011 May; 6(5):e20080. PMID: 21611152
The rotavirus (RV) genome consists of 11 double-stranded RNA segments. Sometimes, partial sequence duplication of an RNA segment leads to a rearranged RNA segment. To specify the impact of rearrangement,...