Matthias G Fischer
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Explore the profile of Matthias G Fischer including associated specialties, affiliations and a list of published articles.
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30
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Recent Articles
1.
Piedade G, Schon M, Lood C, Fofanov M, Wesdorp E, Biggs T, et al.
Nat Commun
. 2024 Oct;
15(1):9192.
PMID: 39448562
The Southern Ocean microbial ecosystem, with its pronounced seasonal shifts, is vulnerable to the impacts of climate change. Since viruses are key modulators of microbial abundance, diversity, and evolution, we...
2.
Koonin E, Fischer M, Kuhn J, Krupovic M
Microbiol Mol Biol Rev
. 2024 Jul;
88(3):e0008623.
PMID: 39023254
SUMMARYPolintons are 15-20 kb-long self-synthesizing transposons that are widespread in eukaryotic, and in particular protist, genomes. Apart from a transposase and a protein-primed DNA polymerase, polintons encode homologs of major...
3.
Krupovic M, Kuhn J, Fischer M, Koonin E
Proc Natl Acad Sci U S A
. 2024 May;
121(23):e2405771121.
PMID: 38805295
The phylum (kingdom , realm ) is a broad assemblage of diverse viruses with comparatively short double-stranded DNA genomes (<50 kbp) that produce icosahedral capsids built from double jelly-roll major...
4.
Krupovic M, Kuhn J, Fischer M, Koonin E
bioRxiv
. 2024 May;
PMID: 38712159
The phylum (kingdom , realm ) is a broad assemblage of diverse viruses with comparatively short double-stranded DNA genomes (<50 kbp) that produce icosahedral capsids built from double jelly-roll major...
5.
Del Arco A, Fischer M, Becks L
Virus Evol
. 2024 Apr;
10(1):veae021.
PMID: 38562952
Tripartite biotic interactions are inherently complex, and the strong interdependence of species and often one-sided exploitation can make these systems vulnerable to extinction. The persistence of species depends then on...
6.
Koslova A, Hackl T, Bade F, Sanchez Kasikovic A, Barenhoff K, Schimm F, et al.
Proc Natl Acad Sci U S A
. 2024 Mar;
121(11):e2314606121.
PMID: 38446847
Endogenous viral elements (EVEs) are common genetic passengers in various protists. Some EVEs represent viral fossils, whereas others are still active. The marine heterotrophic flagellate contains several EVE types related...
7.
Aylward F, Abrahao J, Brussaard C, Fischer M, Moniruzzaman M, Ogata H, et al.
Arch Virol
. 2023 Oct;
168(11):283.
PMID: 37904060
Large DNA viruses in the phylum Nucleocytoviricota, sometimes referred to as "giant viruses" owing to their large genomes and virions, have been the subject of burgeoning interest over the last...
8.
Bellas C, Hackl T, Plakolb M, Koslova A, Fischer M, Sommaruga R
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2300465120.
PMID: 37036967
Eukaryotic genomes contain a variety of endogenous viral elements (EVEs), which are mostly derived from RNA and ssDNA viruses that are no longer functional and are considered to be "genomic...
9.
Roux S, Fischer M, Hackl T, Katz L, Schulz F, Yutin N
Biomolecules
. 2023 Feb;
13(2).
PMID: 36830574
Virophages are small dsDNA viruses that hijack the machinery of giant viruses during the co-infection of a protist (i.e., microeukaryotic) host and represent an exceptional case of "hyperparasitism" in the...
10.
Martin R, Dressler H, Hattab G, Hackl T, Fischer M, Heider D
Comput Struct Biotechnol J
. 2021 Oct;
19:5504-5509.
PMID: 34712396
Due to the highly growing number of available genomic information, the need for accessible and easy-to-use analysis tools is increasing. To facilitate eukaryotic genome annotations, we created MOSGA. In this...