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Sarah Brix

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Articles 11
Citations 258
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Recent Articles
1.
Betz I, Qaiyumi S, Goeritzer M, Thiele A, Brix S, Beyhoff N, et al.
Int J Mol Sci . 2021 Dec; 22(23). PMID: 34884498
Palmitoleic acid (C16:1n7) has been identified as a regulator of physiological cardiac hypertrophy. In the present study, we aimed to investigate the molecular pathways involved in C16:1n7 responses in primary...
2.
Ott C, Jung T, Brix S, John C, Betz I, Foryst-Ludwig A, et al.
Cells . 2021 Apr; 10(4). PMID: 33916597
Cardiac remodeling and contractile dysfunction are leading causes in hypertrophy-associated heart failure (HF), increasing with a population's rising age. A hallmark of aged and diseased hearts is the accumulation of...
3.
Beyhoff N, Lohr D, Foryst-Ludwig A, Klopfleisch R, Brix S, Grune J, et al.
Hypertension . 2019 Jul; 74(2):295-304. PMID: 31291149
Subendocardial damage is among the first cardiac manifestations of hypertension and is already present in asymptomatic disease states. Accordingly, markers of subendocardial impairment may facilitate early detection of cardiac damages...
4.
Grune J, Blumrich A, Brix S, Jeuthe S, Drescher C, Grune T, et al.
Cardiovasc Ultrasound . 2018 Jul; 16(1):10. PMID: 29966517
Background: The assessment of ventricular volumes using conventional echocardiography methods is limited with regards to the need of geometrical assumptions. In the present study, we aimed to evaluate a novel...
5.
Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, et al.
Hypertension . 2018 Feb; 71(4):599-608. PMID: 29437893
Mineralocorticoid receptor antagonists (MRAs) reduce morbidity and mortality in chronic heart failure. Novel nonsteroidal MRAs are currently developed and need to be pharmacologically characterized in comparison to classical steroidal MRAs....
6.
Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, et al.
PLoS Genet . 2018 Jan; 14(1):e1007171. PMID: 29320510
Adipose tissue lipolysis occurs during the development of heart failure as a consequence of chronic adrenergic stimulation. However, the impact of enhanced adipose triacylglycerol hydrolysis mediated by adipose triglyceride lipase...
7.
Beyhoff N, Brix S, Betz I, Klopfleisch R, Foryst-Ludwig A, Krannich A, et al.
J Am Soc Echocardiogr . 2017 Oct; 30(12):1239-1250.e2. PMID: 29066223
Background: The subendocardium is highly vulnerable to damage and is thus affected even in subclinical disease stages. Therefore, methods reflecting subendocardial status are of great clinical relevance for the early...
8.
Brix S, Cantow K, Flemming B, Pohlmann A, Niendorf T, Seeliger E
J Magn Reson Imaging . 2017 Aug; 47(4):1140-1141. PMID: 28758280
No abstract available.
9.
Ban Z, Maurischat P, Benz V, Brix S, Sonnenburg A, Schuler G, et al.
Sci Rep . 2017 Feb; 7:43269. PMID: 28233809
Estrogen receptor alpha (ERα) is a major regulator of metabolic processes in obesity. In this study we aimed to define the relevance of adipose tissue ERα during high-fat diet (HFD)-induced...
10.
Grune J, Benz V, Brix S, Salatzki J, Blumrich A, Hoft B, et al.
J Cardiovasc Pharmacol . 2016 Feb; 67(5):402-11. PMID: 26859196
Pharmacological blockade of mineralocorticoid receptors (MR) is known as an efficacious therapy in chronic heart failure. Therapy with steroidal MR antagonists such as spironolactone or eplerenone (EPL) is often limited...