Sara Svensson Akusjarvi
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Explore the profile of Sara Svensson Akusjarvi including associated specialties, affiliations and a list of published articles.
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14
Citations
333
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Recent Articles
1.
Mikaeloff F, Gelpi M, Escos A, Wang T, Gupta S, Olofsson A, et al.
Adv Sci (Weinh)
. 2025 Feb;
:e2416453.
PMID: 40013867
Risk stratification using multi-omics data deepens understanding of immunometabolism in successfully treated people with HIV (PWH) is inadequately explained. A personalized medicine approach integrating blood cell transcriptomics, plasma proteomics, and...
2.
Ambikan A, Akusjarvi S, Sperk M, Neogi U
Adv Immunol
. 2024 Nov;
164:73-100.
PMID: 39523029
The emergence and re-emergence of infectious diseases present significant global health threats. Understanding their pathogenesis is crucial for developing diagnostics, therapeutics, and preventive strategies. System-level integrative omics analysis offers a...
3.
Akusjarvi S, Zanoni I
Curr Opin Immunol
. 2024 May;
87:102423.
PMID: 38776716
The host immune response against severe acute respiratory syndrome coronavirus 2 includes the induction of a group of natural antiviral cytokines called interferons (IFNs). Although originally recognized for their ability...
4.
Akusjarvi S, Krishnan S, Ambikan A, Mikaeloff F, Ponnan S, Vesterbacka J, et al.
AIDS
. 2023 Feb;
37(7):1023-1033.
PMID: 36779490
Objective: Why people with HIV-1 on ART (PWH ART ) display convoluted metabolism and immune cell functions during prolonged suppressive therapy is not well evaluated. In this study, we aimed...
5.
Biological Aging in People Living with HIV on Successful Antiretroviral Therapy: Do They Age Faster?
Akusjarvi S, Neogi U
Curr HIV/AIDS Rep
. 2023 Jan;
20(2):42-50.
PMID: 36695947
Purpose Of Review: In the absence of a prophylactic/therapeutic vaccine or cure, the most amazing achievement in the battle against HIV was the discovery of effective, well-tolerated combination antiretroviral therapy...
6.
Ambikan A, Yang H, Krishnan S, Akusjarvi S, Gupta S, Lourda M, et al.
Cell Syst
. 2022 Aug;
13(8):665-681.e4.
PMID: 35933992
The clinical outcome and disease severity in coronavirus disease 2019 (COVID-19) are heterogeneous, and the progression or fatality of the disease cannot be explained by a single factor like age...
7.
Akusjarvi S, Krishnan S, Jutte B, Ambikan A, Gupta S, Rodriguez J, et al.
Commun Biol
. 2022 Apr;
5(1):357.
PMID: 35418589
HIV-1 infection induces a chronic inflammatory environment not restored by suppressive antiretroviral therapy (ART). As of today, the effect of viral suppression and immune reconstitution in people living with HIV-1...
8.
Mikaeloff F, Akusjarvi S, Ikomey G, Krishnan S, Sperk M, Gupta S, et al.
Commun Biol
. 2022 Jan;
5(1):27.
PMID: 35017663
Despite successful combination antiretroviral therapy (cART), persistent low-grade immune activation together with inflammation and toxic antiretroviral drugs can lead to long-lasting metabolic flexibility and adaptation in people living with HIV...
9.
Akusjarvi S, Ambikan A, Krishnan S, Gupta S, Sperk M, Vegvari A, et al.
iScience
. 2022 Jan;
25(1):103607.
PMID: 35005552
Natural control of HIV-1 is a characteristic of <1% of HIV-1-infected individuals, so called elite controllers (EC). In this study, we sought to identify signaling pathways associated with the EC...
10.
Appelberg S, Gupta S, Akusjarvi S, Ambikan A, Mikaeloff F, Saccon E, et al.
Emerg Microbes Infect
. 2020 Jul;
9(1):1748-1760.
PMID: 32691695
How severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections engage cellular host pathways and innate immunity in infected cells remains largely elusive. We performed an integrative proteo-transcriptomics analysis in SARS-CoV-2 infected...