Sara R Martins-Neves
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Explore the profile of Sara R Martins-Neves including associated specialties, affiliations and a list of published articles.
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9
Citations
280
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Recent Articles
1.
Martins-Neves S, Sampaio-Ribeiro G, Gomes C
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37176108
Osteosarcoma is a highly malignant bone tumor derived from mesenchymal cells that contains self-renewing cancer stem cells (CSCs), which are responsible for tumor progression and chemotherapy resistance. Understanding the signaling...
2.
Martins-Neves S, Sampaio-Ribeiro G, Gomes C
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232719
Osteosarcoma is amongst the most prevalent bone sarcomas and majorly afflicts children and adolescents. Therapeutic regimens based on the triad of doxorubicin, cisplatin and methotrexate have been used as the...
3.
Martins-Neves S, Cleton-Jansen A, Gomes C
Pharmacol Res
. 2018 Oct;
137:193-204.
PMID: 30316903
The development of local recurrence and metastatic disease, most probably attributable to the intrinsic or acquired resistance of tumor cells to standard therapy, still constitute the major clinical problem preventing...
4.
Martins-Neves S, Paiva-Oliveira D, Fontes-Ribeiro C, Bovee J, Cleton-Jansen A, Gomes C
Cancer Lett
. 2017 Nov;
414:1-15.
PMID: 29126913
Wnt/β-catenin or canonical Wnt signaling pathway regulates the self-renewal of cancer stem-like cells (CSCs) and is involved in tumor progression and chemotherapy resistance. Previously, we reported that this pathway is...
5.
Paiva-Oliveira D, Martins-Neves S, Abrunhosa A, Fontes-Ribeiro C, Gomes C
Cancer Chemother Pharmacol
. 2017 Nov;
81(1):49-63.
PMID: 29086064
Purpose: Osteosarcoma is the most common primary bone tumour appearing in children and adolescents. Recent studies demonstrate that osteosarcoma possesses a stem-like cell subset, so-called cancer stem-like cells, refractory to...
6.
Martins-Neves S, Paiva-Oliveira D, Wijers-Koster P, Abrunhosa A, Fontes-Ribeiro C, Bovee J, et al.
Cancer Lett
. 2015 Nov;
370(2):286-95.
PMID: 26577806
Development of resistance represents a major drawback in osteosarcoma treatment, despite improvements in overall survival. Treatment failure and tumor progression have been attributed to pre-existing drug-resistant clones commonly assigned to...
7.
Martins-Neves S, Corver W, Paiva-Oliveira D, van den Akker B, Briaire-de-Bruijn I, Bovee J, et al.
J Cell Physiol
. 2015 Sep;
231(4):876-86.
PMID: 26332365
Osteosarcoma is a bone tumor, displaying significant cellular and histological heterogeneity and a complex genetic phenotype. Although multiple studies strongly suggest the presence of cancer stem cells in osteosarcoma, a...
8.
Goncalves C, Martins-Neves S, Paiva-Oliveira D, Oliveira V, Fontes-Ribeiro C, Gomes C
Life Sci
. 2015 Mar;
130:47-56.
PMID: 25818183
Aims: Osteosarcoma is the most common pediatric bone malignancy with high propensity to metastasize and relapse. Emerging evidence suggest that osteosarcoma is sustained by a subset of self-renewing cancer stem...
9.
Martins-Neves S, Lopes A, do Carmo A, Paiva A, Simoes P, Abrunhosa A, et al.
BMC Cancer
. 2012 Apr;
12:139.
PMID: 22475227
Background: Osteosarcoma is a bone-forming tumor of mesenchymal origin that presents a clinical pattern that is consistent with the cancer stem cell model. Cells with stem-like properties (CSCs) have been...