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Sara Maimouni

Explore the profile of Sara Maimouni including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 234
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Recent Articles
1.
Han H, Efem R, Rosati B, Lu K, Maimouni S, Jiang Y, et al.
Elife . 2025 Mar; 13. PMID: 40067762
Most human pancreatic ductal adenocarcinoma (PDAC) are not infiltrated with cytotoxic T cells and are highly resistant to immunotherapy. Over 90% of PDAC have oncogenic KRAS mutations, and phosphoinositide 3-kinases...
2.
Han H, Efem R, Rosati B, Lu K, Maimouni S, Jiang Y, et al.
bioRxiv . 2023 Aug; PMID: 37546948
Most human pancreatic ductal adenocarcinoma (PDAC) are not infiltrated with cytotoxic T cells and are highly resistant to immunotherapy. Over 90% of PDAC have oncogenic KRAS mutations, and phosphoinositide 3-kinases...
3.
Dai W, Shen J, Yan J, Bott A, Maimouni S, Daguplo H, et al.
J Clin Invest . 2022 Oct; 132(24). PMID: 36256480
Glutamine synthetase (GS) catalyzes de novo synthesis of glutamine that facilitates cancer cell growth. In the liver, GS functions next to the urea cycle to remove ammonia waste. As a...
4.
Maimouni S, Lee M, Sung Y, Hall M, Roy A, Ouaari C, et al.
Oncotarget . 2021 Nov; 12(22):2305-2306. PMID: 34733422
[This corrects the article DOI: 10.18632/oncotarget.26600.].
5.
Wang F, Zhang Y, Shen J, Yang B, Dai W, Yan J, et al.
Cell Mol Gastroenterol Hepatol . 2021 Jan; 11(5):1369-1385. PMID: 33482392
Background And Aims: TRIM21 is a ubiquitin E3 ligase that is implicated in numerous biological processes including immune response, cell metabolism, redox homeostasis, and cancer development. We recently reported that...
6.
Su X, Chiles E, Maimouni S, Wondisford F, Zong W, Song C
Anal Chem . 2020 Mar; 92(7):4829-4837. PMID: 32125145
A large proportion of the complexity and redundancy of LC-MS metabolomics data comes from adduct formation. To reduce such redundancy, many tools have been developed to recognize and annotate adduct...
7.
Bott A, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang Y, et al.
Cell Rep . 2019 Oct; 29(5):1287-1298.e6. PMID: 31665640
Glutamine is thought to play an important role in cancer cells by being deaminated via glutaminolysis to α-ketoglutarate (aKG) to fuel the tricarboxylic acid (TCA) cycle. Supporting this notion, aKG...
8.
Bott A, Maimouni S, Zong W
Cancers (Basel) . 2019 Jun; 11(6). PMID: 31167399
Metabolic programs are known to be altered in cancers arising from various tissues. Malignant transformation can alter signaling pathways related to metabolism and increase the demand for both energy and...
9.
Maimouni S, Lee M, Sung Y, Hall M, Roy A, Ouaari C, et al.
Oncotarget . 2019 Mar; 10(17):1606-1624. PMID: 30899431
RARRES1, a retinoic acid regulated carboxypeptidase inhibitor associated with fatty acid metabolism, stem cell differentiation and tumorigenesis is among the most commonly methylated loci in multiple cancers but has no...
10.
Maimouni S, Issa N, Cheng S, Ouaari C, Cheema A, Kumar D, et al.
PLoS One . 2018 Dec; 13(12):e0208756. PMID: 30557378
Retinoic acid receptor responder 1 (RARRES1) is silenced in many cancers and is differentially expressed in metabolism associated diseases, such as hepatic steatosis, hyperinsulinemia and obesity. Here we report a...