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Sara de Mateo

Explore the profile of Sara de Mateo including associated specialties, affiliations and a list of published articles. Areas
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Citations 922
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Recent Articles
1.
Cavallo F, Mirza K, de Mateo S, Miglietta L, Rodriguez-Manzano J, Nikolic K, et al.
Biosensors (Basel) . 2022 Jul; 12(7). PMID: 35884340
This paper presents a fully automated point-of-care device for protein quantification using short-DNA aptamers, where no manual sample preparation is needed. The device is based on our novel aptamer-based methodology...
2.
Jahin M, Fenech-Salerno B, Moser N, Georgiou P, Flanagan J, Toumazou C, et al.
Annu Int Conf IEEE Eng Med Biol Soc . 2021 Dec; 2021:7385-7389. PMID: 34892804
The growing cancer burden necessitates the development of cost-effective solutions that provide rapid, precise and personalised information to improve patient outcome. The aim of this study was to develop a...
3.
Cavallo F, Mirza K, de Mateo S, Nikolic K, Rodriguez-Manzano J, Toumazou C
ACS Sens . 2021 Mar; 6(3):709-715. PMID: 33650854
Protein quantification is traditionally performed through enzyme-linked immunosorbent assay (ELISA), which involves long preparation times. To overcome this, new approaches use aptamers as an alternative to antibodies. In this paper,...
4.
Gibani M, Toumazou C, Sohbati M, Sahoo R, Karvela M, Hon T, et al.
Lancet Microbe . 2020 Sep; 1(7):e300-e307. PMID: 32964211
Background: Access to rapid diagnosis is key to the control and management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Laboratory RT-PCR testing is the current standard of care but...
5.
Dyar K, Lutter D, Artati A, Ceglia N, Liu Y, Armenta D, et al.
Cell . 2018 Sep; 174(6):1571-1585.e11. PMID: 30193114
Metabolic diseases are often characterized by circadian misalignment in different tissues, yet how altered coordination and communication among tissue clocks relate to specific pathogenic mechanisms remains largely unknown. Applying an...
6.
de Mateo S, Sassone-Corsi P
Semin Cell Dev Biol . 2014 Apr; 29:84-92. PMID: 24755166
The spermatogenic process relays in highly regulated gene expression mechanisms at the transcriptional and post-transcriptional levels to generate the male gamete that is needed for the perpetuation of the species....
7.
Eckel-Mahan K, Patel V, de Mateo S, Orozco-Solis R, Ceglia N, Sahar S, et al.
Cell . 2013 Dec; 155(7):1464-78. PMID: 24360271
Circadian rhythms and cellular metabolism are intimately linked. Here, we reveal that a high-fat diet (HFD) generates a profound reorganization of specific metabolic pathways, leading to widespread remodeling of the...
8.
de Mateo S, Estanyol J, Oliva R
Methods Mol Biol . 2012 Sep; 927:411-22. PMID: 22992932
Proteomics is the study of the proteins of cells or tissues. Sperm proteomics aims at the identification of the proteins that compose the sperm cell and the study of their...
9.
Peruquetti R, de Mateo S, Sassone-Corsi P
PLoS One . 2012 Aug; 7(8):e42695. PMID: 22900038
Spermatogenesis is a complex differentiation process that involves genetic and epigenetic regulation, sophisticated hormonal control, and extensive structural changes in male germ cells. RNA nuclear and cytoplasmic bodies appear to...
10.
de Mateo S, Castillo J, Estanyol J, Ballesca J, Oliva R
Proteomics . 2011 Jun; 11(13):2714-26. PMID: 21630459
Generating a catalogue of sperm nuclear proteins is an important first step towards the clarification of the function of the paternal chromatin transmitted to the oocyte upon fertilization. With this...