Sara Crespo Yanguas
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Explore the profile of Sara Crespo Yanguas including associated specialties, affiliations and a list of published articles.
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28
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671
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Recent Articles
1.
Cooreman A, Van Campenhout R, Crespo Yanguas S, Gijbels E, Leroy K, Pieters A, et al.
Int J Mol Sci
. 2020 Sep;
21(18).
PMID: 32906817
Connexins are goal keepers of tissue homeostasis, including in the liver. As a result, they are frequently involved in disease. The current study was set up to investigate the effects...
2.
Van Campenhout R, Crespo Yanguas S, Cooreman A, Gijbels E, Leroy K, Vilas-Boas V, et al.
Biomolecules
. 2019 Oct;
9(10).
PMID: 31652629
Adherens junctions, consisting of cadherins and catenins, are a group of cell-to-cell junctions that mediate mechanistic linkage between neighboring cells. By doing so, adherens junctions ensure direct intercellular contact and...
3.
Crespo Yanguas S, Da Silva T, Pereira I, Maes M, Willebrords J, Shestopalov V, et al.
Arch Toxicol
. 2018 Jul;
92(8):2607-2627.
PMID: 29987408
Liver fibrosis is the final common pathway for almost all causes of chronic liver injury. This chronic disease is characterized by excessive deposition of extracellular matrix components mainly due to...
4.
Crespo Yanguas S, Da Silva T, Pereira I, Willebrords J, Maes M, Nogueira M, et al.
Int J Mol Sci
. 2018 Mar;
19(3).
PMID: 29534516
Although a plethora of signaling pathways are known to drive the activation of hepatic stellate cells in liver fibrosis, the involvement of connexin-based communication in this process remains elusive. Connexin43...
5.
Willebrords J, Maes M, Pereira I, Da Silva T, Mollica Govoni V, Lopes V, et al.
Biochim Biophys Acta Mol Basis Dis
. 2017 Dec;
1864(3):819-830.
PMID: 29246445
Pannexins are transmembrane proteins that form communication channels connecting the cytosol of an individual cell with its extracellular environment. A number of studies have documented the presence of pannexin1 in...
6.
Willebrords J, Cogliati B, Pereira I, Da Silva T, Crespo Yanguas S, Maes M, et al.
Sci Rep
. 2017 Aug;
7(1):8268.
PMID: 28811572
While gap junctions mediate intercellular communication and support liver homeostasis, connexin hemichannels are preferentially opened by pathological stimuli, including inflammation and oxidative stress. The latter are essential features of non-alcoholic...
7.
Willebrords J, Maes M, Crespo Yanguas S, Vinken M
Pharmacol Ther
. 2017 Jul;
180:144-160.
PMID: 28720428
While gap junctions support the exchange of a number of molecules between neighboring cells, connexin hemichannels provide communication between the cytosol and the extracellular environment of an individual cell. The...
8.
Maes M, Crespo Yanguas S, Willebrords J, Weemhoff J, Da Silva T, Decrock E, et al.
Toxicol Lett
. 2017 Jul;
278:30-37.
PMID: 28687253
Historically, connexin hemichannels have been considered as structural precursors of gap junctions. However, accumulating evidence points to independent roles for connexin hemichannels in cellular signaling by connecting the intracellular compartment...
9.
Maes M, McGill M, Da Silva T, Abels C, Lebofsky M, Weemhoff J, et al.
Arch Toxicol
. 2017 Mar;
91(5):2263-2264.
PMID: 28243680
No abstract available.
10.
Tiburcio T, Willebrords J, Da Silva T, Pereira I, Nogueira M, Crespo Yanguas S, et al.
Clin Exp Pharmacol Physiol
. 2016 Nov;
44(2):197-206.
PMID: 27859493
Non-alcoholic steatohepatitis is a highly prevalent liver pathology featured by hepatocellular fat deposition and inflammation. Connexin32, which is the major building block of hepatocellular gap junctions, has a protective role...