Sara Bermudez
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Explore the profile of Sara Bermudez including associated specialties, affiliations and a list of published articles.
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13
Citations
260
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Recent Articles
1.
Wang P, Li Z, Kim S, Xu H, Huang H, Yang C, et al.
Life Sci Alliance
. 2024 Aug;
7(10).
PMID: 39111820
The mRNA 5'cap-binding eukaryotic translation initiation factor 4E (eIF4E) plays a critical role in the control of mRNA translation in health and disease. One mechanism of regulation of eIF4E activity...
2.
Ribeiro F, Cozachenco D, Argyrousi E, Staniszewski A, Wiebe S, Calixtro J, et al.
Alzheimers Dement
. 2024 Jun;
20(8):5398-5410.
PMID: 38934107
Introduction: Impaired brain protein synthesis, synaptic plasticity, and memory are major hallmarks of Alzheimer's disease (AD). The ketamine metabolite (2R,6R)-hydroxynorketamine (HNK) has been shown to modulate protein synthesis, but its...
3.
Khayrullina G, Bermudez S, Hopkins D, Yauger Y, Byrnes K
PLoS One
. 2023 Mar;
18(3):e0281045.
PMID: 36897852
Reactive oxygen species (ROS) are a contributing factor to impaired function and pathology after spinal cord injury (SCI). The NADPH oxidase (NOX) enzyme is a key source of ROS; there...
4.
Saviuk N, Chong Y, Wang P, Bermudez S, Zhao Z, Bhaskaran A, et al.
Cell Rep
. 2022 Jun;
39(10):110911.
PMID: 35675781
Genetic perturbances in translational regulation result in defects in cerebellar motor learning; however, little is known about the role of translational mechanisms in the regulation of cerebellar plasticity. We show...
5.
Aguilar-Valles A, De Gregorio D, Matta-Camacho E, Eslamizade M, Khlaifia A, Skaleka A, et al.
Nature
. 2020 Dec;
590(7845):315-319.
PMID: 33328636
Effective pharmacotherapy for major depressive disorder remains a major challenge, as more than 30% of patients are resistant to the first line of treatment (selective serotonin reuptake inhibitors). Sub-anaesthetic doses...
6.
Ahualli S, Bermudez S, Carrique F, Jimenez M, Delgado A
Polymers (Basel)
. 2020 Sep;
12(9).
PMID: 32942664
Interest in the electrical properties of the interface between soft (or polymer-grafted) nanoparticles and solutions is considerable. Of particular significance is the case of polyelectrolyte-coated particles, mainly taking into account...
7.
Yauger Y, Bermudez S, Moritz K, Glaser E, Stoica B, Byrnes K
J Neuroinflammation
. 2019 Feb;
16(1):41.
PMID: 30777083
Background: Excessive iron contributes to oxidative stress after central nervous system injury. NADPH oxidase (NOX) enzymes are upregulated in microglia after pro-inflammatory activation and contribute to oxidative stress. The relationship...
8.
von Leden R, Moritz K, Bermudez S, Jaiswal S, Wilson C, Dardzinski B, et al.
Neurosci Lett
. 2018 Oct;
690:23-28.
PMID: 30296507
Aging results in increased activation of inflammatory glial cells and decreased neuronal viability following spinal cord injury (SCI). Metabolism and transport of glucose is also decreased with age, although the...
9.
Brabazon F, Bermudez S, Shaughness M, Khayrullina G, Byrnes K
PLoS One
. 2018 Aug;
13(8):e0201878.
PMID: 30148836
Microglia are the macrophages of the central nervous system (CNS), which function to monitor and maintain homeostasis. Microglial activation occurs after CNS injury, infection or disease. Prolonged microglial activation is...
10.
Bermudez S, Khayrullina G, Zhao Y, Byrnes K
Mol Cell Neurosci
. 2016 Nov;
77:53-64.
PMID: 27729244
Spinal cord injury (SCI) results in both acute and chronic inflammation, as a result of activation of microglia, invasion of macrophages and activation of the NADPH oxidase (NOX) enzyme. The...