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Santiyagu M Savarimuthu

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Articles 4
Citations 76
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Recent Articles
1.
Wright C, Larsen J, Hayward N, Martins M, Tan M, Davidson M, et al.
Genes Chromosomes Cancer . 2010 Jun; 49(8):688-98. PMID: 20544843
Asbestos-related lung cancer accounts for 4-12% of all lung cancers worldwide. Since putative mechanisms of carcinogenesis differ between asbestos and tobacco induced lung cancers, tumors induced by the two agents...
2.
Chen L, Meyers D, Javorsky G, Burstow D, Lolekha P, Lucas M, et al.
Pharmacogenet Genomics . 2007 Dec; 17(11):941-9. PMID: 18075464
Objective: Administration of the beta-adrenergic receptor blocker carvedilol to patients with chronic heart failure leads to clinically significant benefits, including improvement in left ventricular systolic function in some, but not...
3.
Molenaar P, Savarimuthu S, Sarsero D, Chen L, Semmler A, Carle A, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2007 Feb; 375(1):11-28. PMID: 17295024
Activation of either coexisting beta1- or beta2 -adrenoceptors with noradrenaline or adrenaline, respectively, causes maximum increases of contractility of human atrial myocardium. Previous biochemical work with the beta2 -selective agonist...
4.
Molenaar P, Rabnott G, Yang I, Fong K, Savarimuthu S, Li L, et al.
J Am Coll Cardiol . 2002 Oct; 40(7):1275-82. PMID: 12383575
Objective: The goal of this study was to determine whether the cardiostimulant effects of the endogenous beta(1)-adrenergic receptor (AR) agonist, (-)-norepinephrine are modified by polymorphic (Serine49Glycine [Ser49Gly], Glycine389Arginine [Gly389Arg]) variants...