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Santhosh A Upadhyaya

Explore the profile of Santhosh A Upadhyaya including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 281
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Recent Articles
1.
Simoneau J, Robertson P, Muraszko K, Maher C, Garton H, Calvert R, et al.
J Natl Compr Canc Netw . 2024 Sep; 22(7). PMID: 39236755
Tissue-agnostic, molecularly targeted therapies are becoming increasingly common in cancer treatment. The molecular drivers of some classes and subclasses of tumors are rapidly being uncovered in an era of deep...
2.
Carey S, Huang J, Myers J, Mostafavi R, Orr B, Dhanda S, et al.
Pediatr Blood Cancer . 2024 Jul; 71(10):e31208. PMID: 39034595
Background: Survival data for recurrent pediatric atypical teratoid rhabdoid tumor (ATRT) and its association to molecular groups are extremely limited. Methods: Single-institution retrospective study of 64 children less than 21 ...
3.
Lee J, Tran Q, McGee R, Perrino M, Upadhyaya S, Hanzlik E, et al.
Neuropathol Appl Neurobiol . 2024 Mar; 50(2):e12971. PMID: 38488196
No abstract available.
4.
Roberts H, Ji S, Picca A, Sanson M, Garcia M, Snuderl M, et al.
Acta Neuropathol . 2023 Oct; 146(6):849-852. PMID: 37851269
No abstract available.
5.
Hargrave D, Terashima K, Hara J, Kordes U, Upadhyaya S, Sahm F, et al.
J Clin Oncol . 2023 Aug; 41(33):5174-5183. PMID: 37643378
Purpose: V600 mutation is detected in 5%-10% of pediatric high-grade gliomas (pHGGs), and effective treatments are limited. In previous trials, dabrafenib as monotherapy or in combination with trametinib demonstrated activity...
6.
Blackburn P, McGee R, Mostafavi R, Carroll A, Mikhail F, Armstrong G, et al.
Genes Chromosomes Cancer . 2023 Aug; 63(1):e23195. PMID: 37548271
Rhabdoid Tumor Predisposition Syndrome 1 (RTPS1) confers an increased risk of developing rhabdoid tumors and is caused by germline mutations in SMARCB1. RTPS1 should be evaluated in all individuals with...
7.
Tran Q, Upadhyaya S, Billups C, Onar-Thomas A, Alom M, Carey S, et al.
Acta Neuropathol . 2023 Jul; 146(3):543-545. PMID: 37522896
No abstract available.
8.
Chiang J, Bagchi A, Li X, Dhanda S, Huang J, Pinto S, et al.
Neuro Oncol . 2023 Jul; 26(1):178-190. PMID: 37503880
Background: High-grade gliomas (HGG) in young children pose a challenge due to favorable but unpredictable outcomes. While retrospective studies broadened our understanding of tumor biology, prospective data is lacking. Methods:...
9.
Paassen I, Williams J, Rios Arceo C, Ringnalda F, Mercer K, Buhl J, et al.
Oncogene . 2023 Apr; 42(20):1661-1671. PMID: 37020038
Atypical teratoid/rhabdoid tumors (ATRTs) represent a rare, but aggressive pediatric brain tumor entity. They are genetically defined by alterations in the SWI/SNF chromatin remodeling complex members SMARCB1 or SMARCA4. ATRTs...
10.
Liu A, Dhanda S, Lin T, Sioson E, Vasilyeva A, Gudenas B, et al.
Acta Neuropathol . 2022 Aug; 144(4):733-746. PMID: 35982322
Methylation profiling has radically transformed our understanding of tumors previously called central nervous system primitive neuro-ectodermal tumors (CNS-PNET). While this marks a momentous step toward defining key differences, reclassification has...