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Santhanam Shanmughapriya

Explore the profile of Santhanam Shanmughapriya including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 2188
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Recent Articles
1.
Ponnusamy T, Velusamy P, Shanmughapriya S
Mitochondrion . 2024 Apr; 76:101877. PMID: 38599304
Mitochondrial Ca uptake is essential in regulating bioenergetics, cell death, and cytosolic Ca transients. Mitochondrial Calcium Uniporter (MCU) mediates the mitochondrial Ca uptake. Though MCU regulation by MICUs is unequivocally...
2.
Ponnusamy T, Velusamy P, Kumar A, Morris D, Zhang X, Ning G, et al.
Res Sq . 2023 Jul; PMID: 37502932
Calcium (Ca) uptake by mitochondria is essential in regulating bioenergetics, cell death, and cytosolic Ca transients. Mitochondrial Calcium Uniporter (MCU) mediates the mitochondrial Ca uptake. MCU is a heterooligomeric complex...
3.
Sumaiya K, Ponnusamy T, Natarajaseenivasan K, Shanmughapriya S
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36613495
The aberrant increase in cardio-metabolic diseases over the past couple of decades has drawn researchers' attention to explore and unveil the novel mechanisms implicated in cardiometabolic diseases. Recent evidence disclosed...
4.
Natarajaseenivasan K, Garcia A, Velusamy P, Shanmughapriya S, Langford D
iScience . 2022 Nov; 25(11):105407. PMID: 36389000
Disturbances in lipid metabolism in the CNS contribute to neurodegeneration and cognitive impairments. Through tight metabolic coupling, astrocytes provide energy to neurons by delivering lactate and cholesterol and by taking...
5.
Muthukumaran N, Velusamy P, Akino Mercy C, Langford D, Natarajaseenivasan K, Shanmughapriya S
J Pers Med . 2022 Aug; 12(8). PMID: 36013278
To adapt to the tumor environment or to escape chemotherapy, cancer cells rapidly reprogram their metabolism. The hallmark biochemical phenotype of cancer cells is the shift in metabolic reprogramming towards...
6.
Kang Y, Datta P, Shanmughapriya S, Ozbolat I
ACS Appl Bio Mater . 2022 Jan; 3(9):5552-5573. PMID: 35021789
The exact mechanistic understanding of cancer metastasis continues to be unknown, although it is a major cause of death worldwide. Along with the tumor mass, the tumor microenvironment also contributes...
7.
Sumaiya K, Langford D, Natarajaseenivasan K, Shanmughapriya S
Pharmacol Ther . 2021 Oct; 233:108024. PMID: 34673115
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated by activated T cells, but in...
8.
Bisserier M, Shanmughapriya S, Rai A, Gonzalez C, Brojakowska A, Garikipati V, et al.
J Am Heart Assoc . 2021 Oct; 10(21):e022055. PMID: 34666498
Background Space travel-associated stressors such as microgravity or radiation exposure have been reported in astronauts after short- and long-duration missions aboard the International Space Station. Despite risk mitigation strategies, adverse...
9.
Natarajaseenivasan K, Shanmughapriya S, Velusamy P, Sayre M, Garcia A, Mas Gomez N, et al.
Transl Neurodegener . 2020 Aug; 9(1):32. PMID: 32746944
Background: Diseases and disorders with a chronic neuroinflammatory component are often linked with changes in brain metabolism. Among neurodegenerative disorders, people living with human immunodeficiency virus (HIV) and Alzheimer's disease...
10.
Shanmughapriya S, Langford D, Natarajaseenivasan K
Ageing Res Rev . 2020 Jul; 62:101128. PMID: 32712108
Neurons and glia maintain central nervous system (CNS) homeostasis through diverse mechanisms of intra- and intercellular signaling. Some of these interactions include the exchange of soluble factors between cells via...