Sanja Sviben
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Explore the profile of Sanja Sviben including associated specialties, affiliations and a list of published articles.
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23
Citations
550
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Recent Articles
1.
Sun Z, Kwon J, Ren Y, Chen S, Walker C, Lu X, et al.
Science
. 2024 Aug;
385(6708):adl2992.
PMID: 39088624
Late-onset Alzheimer's disease (LOAD) is the most common form of Alzheimer's disease (AD). However, modeling sporadic LOAD that endogenously captures hallmark neuronal pathologies such as amyloid-β (Aβ) deposition, tau tangles,...
2.
Sviben S, Polino A, Melena I, Hughes J
J Cell Sci
. 2024 May;
137(20).
PMID: 38804679
The definitive demonstration of protein localization on primary cilia has been a challenge for cilia biologists. Primary cilia are solitary thread-like projections that have a specialized protein composition, but as...
3.
Sviben S, Polino A, Melena I, Hughes J
bioRxiv
. 2024 Feb;
PMID: 38405740
The definitive demonstration of protein localization on primary cilia has been a challenge for cilia biologists. Primary cilia are solitary thread-like projections that contain specialized protein composition, but as the...
4.
Li J, Moretti F, Hidvegi T, Sviben S, Fitzpatrick J, Sundaramoorthi H, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Feb;
17(6):1007-1024.
PMID: 38336172
Background & Aims: In the classic form of α1-antitrypsin deficiency (ATD), the misfolded α1-antitrypsin Z (ATZ) variant accumulates in the endoplasmic reticulum (ER) of liver cells. A gain-of-function proteotoxic mechanism...
5.
Skeffington A, Fischer A, Sviben S, Brzezinka M, Gorka M, Bertinetti L, et al.
Nat Commun
. 2023 Jun;
14(1):3749.
PMID: 37353496
Coccolithophores are globally abundant, calcifying microalgae that have profound effects on marine biogeochemical cycles, the climate, and life in the oceans. They are characterized by a cell wall of CaCO...
6.
Sun Z, Kwon J, Ren Y, Chen S, Cates K, Lu X, et al.
bioRxiv
. 2023 Jun;
PMID: 37292658
Alzheimer's disease (AD) is a neurodegenerative disorder that primarily affects elderly individuals, and is characterized by hallmark neuronal pathologies including extracellular amyloid-β (Aβ) plaque deposition, intracellular tau tangles, and neuronal...
7.
Polino A, Sviben S, Melena I, Piston D, Hughes J
Proc Natl Acad Sci U S A
. 2023 May;
120(22):e2302624120.
PMID: 37205712
Human islet primary cilia are vital glucose-regulating organelles whose structure remains uncharacterized. Scanning electron microscopy (SEM) is a useful technique for studying the surface morphology of membrane projections like cilia,...
8.
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a -dependent manner in mice
Parhizkar S, Gent G, Chen Y, Rensing N, Gratuze M, Strout G, et al.
Sci Transl Med
. 2023 Apr;
15(693):eade6285.
PMID: 37099634
Sleep loss is associated with cognitive decline in the aging population and is a risk factor for Alzheimer's disease (AD). Considering the crucial role of immunomodulating genes such as that...
9.
Hou J, Zhou Y, Cai Z, Terekhova M, Swain A, Andhey P, et al.
Cell Rep
. 2023 Mar;
42(4):112293.
PMID: 36952346
Demyelination is a hallmark of multiple sclerosis, leukoencephalopathies, cerebral vasculopathies, and several neurodegenerative diseases. The cuprizone mouse model is widely used to simulate demyelination and remyelination occurring in these diseases....
10.
Polino A, Sviben S, Melena I, Piston D, Hughes J
bioRxiv
. 2023 Feb;
PMID: 36824775
Human islet primary cilia are vital glucose-regulating organelles whose structure remains uncharacterized. Scanning electron microscopy (SEM) is a useful technique for studying the surface morphology of membrane projections like primary...