Sang-Won Hong
Overview
Explore the profile of Sang-Won Hong including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
422
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Recent Articles
1.
Hong S, Jung K, Lee H, Son M, Yan H, Kang N, et al.
Carcinogenesis
. 2013 May;
34(9):2156-69.
PMID: 23671132
SB365, Pulsatilla saponin D isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer. However, the molecular mechanisms...
2.
Jung K, Ryu Y, Lee H, Lee H, Son M, Yan H, et al.
Int J Oncol
. 2013 Apr;
42(6):2001-8.
PMID: 23588860
Peyronie's disease (PD) is fibrosis localized in the tunica albuginea that is characterized by penile deformity and curvature. The pathogenesis of this disease remains unclear even though transforming growth factor-β...
3.
Hong S, Jung K, Park B, Zheng H, Lee H, Choi M, et al.
Cancer Lett
. 2013 Jan;
332(1):74-82.
PMID: 23348694
Among many cancer therapeutic targets, c-Met receptor tyrosine kinase has recently given particular attention. This kinase and its ligand, hepatocyte growth factor (HGF), play a central role in cell proliferation...
4.
Park B, Jung K, Yun S, Hong S, Ryu J, Jung H, et al.
Cancer Lett
. 2013 Jan;
331(2):158-66.
PMID: 23340177
c-Met receptor tyrosine kinase and its ligand, hepatocyte growth factor (HGF), have been reported to be involved in tumorigenesis and metastatic progression. We synthesized a novel triazolopyridazine derivative KRC-327 which...
5.
Li G, Jung K, Lee H, Son M, Seo J, Hong S, et al.
Cancer Lett
. 2012 Oct;
329(1):59-67.
PMID: 23085493
Abnormal activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway is an essential step for the formation and growth of tumors in humans. HS-106 is an imidazopyridine derivative that inhibits the kinase...
6.
Son M, Jung K, Hong S, Lee H, Zheng H, Choi M, et al.
Food Chem
. 2012 Sep;
136(1):26-33.
PMID: 23017388
Pulsatilla koreana has been used as a traditional medicine for the treatment of several diseases. The purpose of this study was to determine if SB365, Pulsatilla saponin D isolated from...
7.
Hong S, Jung K, Choi M, Kim D, Lee H, Zheng H, et al.
Int J Oncol
. 2012 Sep;
41(5):1715-22.
PMID: 22941304
The anticancer effect of a new pyrazole derivative, KI-10F (2-(4-(2-(4-(dimethylamino) phenyl)pyridin-4-yl)-5-(3-methoxy-5-methylphenyl)-1H-pyrazol‑1-yl) acetonitrile)•3.5HCl) was evaluated in human colon cancer cells. KI-10F strongly suppressed the growth of human colon cancer cells and...
8.
Hong S, Jung K, Lee H, Choi M, Son M, Zheng H, et al.
Cancer Sci
. 2012 Aug;
103(11):1929-37.
PMID: 22909393
Identification of small molecules that safely inhibit cancer progression is critical for cancer therapeutics. Saponins exhibit cytostatic and cytotoxic activity against various cancer cells, but the mechanism is not well...
9.
Jung K, Zheng H, Jeong Y, Choi M, Lee H, Hong S, et al.
Cancer Lett
. 2012 Aug;
328(1):176-87.
PMID: 22902995
Dysregulation of the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signaling pathway frequently instigates tumorigenesis leading to hepatocellular carcinoma (HCC). We synthesized N-(5-(3-(3-methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide (HS-104), a novel PI3K inhibitor, and investigated its in vitro anticancer...
10.
Hong S, Lee H, Jung K, Lee H, Hong S
Arch Pharm Res
. 2012 Aug;
35(6):1099-105.
PMID: 22870820
Fucoidan, a sulfated polysaccharide extracted from various brown seaweeds, possesses a wide range of pharmacological properties. In this study, we investigated the protective effect of fucoidan on acetaminophen-induced acute liver...