Sandy Mattijssen
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Explore the profile of Sandy Mattijssen including associated specialties, affiliations and a list of published articles.
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24
Citations
543
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Recent Articles
1.
Ranjan A, Mattijssen S, Charlly N, Gallardo I, Pitman L, Coleman J, et al.
Nucleic Acids Res
. 2025 Feb;
53(3).
PMID: 39898547
LARP4 interacts with poly(A)-binding protein (PABP) to protect messenger RNAs (mRNAs) from deadenylation and decay, and recent data indicate it can direct the translation of functionally related mRNA subsets. LARP4...
2.
Ranjan A, Mattijssen S, Charlly N, Gallardo I, Pitman L, Coleman J, et al.
bioRxiv
. 2024 Nov;
PMID: 39554137
LARP4 interacts with poly(A)-binding protein (PABP) to protect mRNAs from deadenylation and decay, and recent data indicate it can direct the translation of functionally related mRNA subsets. LARP4 was known...
3.
Mattijssen S, Kerkhofs K, Stephen J, Yang A, Han C, Tadafumi Y, et al.
bioRxiv
. 2024 Feb;
PMID: 38410490
RNA polymerase III (Pol III, POLR3) synthesizes tRNAs and other small non-coding RNAs. Human pathogenic variants cause a range of developmental disorders, recapitulated in part by mouse models, yet some...
4.
Iben J, Li T, Mattijssen S, Maraia R
Methods Mol Biol
. 2023 Oct;
2723:285-301.
PMID: 37824077
The polyadenylation of the 3' ends of messenger RNAs is an important regulator of stability and translation. We developed the single-molecule poly(A) tail sequencing method, SM-PATseq, to assay tail lengths...
5.
Whitlock J, Leikina E, Melikov K, de Castro L, Mattijssen S, Maraia R, et al.
Nat Commun
. 2023 Feb;
14(1):616.
PMID: 36739273
Multinucleated osteoclasts, essential for skeletal remodeling in health and disease, are formed by the fusion of osteoclast precursors, where each fusion event raises their bone-resorbing activity. Here we show that...
6.
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules T, Iben J, et al.
Nucleic Acids Res
. 2022 Aug;
50(16):9534-9547.
PMID: 35979957
La-related proteins (LARPs) comprise a family of RNA-binding proteins involved in a wide range of posttranscriptional regulatory activities. LARPs share a unique tandem of two RNA-binding domains, La motif (LaM)...
7.
Khalique A, Mattijssen S, Maraia R
RNA
. 2021 Dec;
28(3):418-432.
PMID: 34930808
The 22 mitochondrial and ∼45 cytosolic tRNAs in human cells contain several dozen different post-transcriptional modified nucleotides such that each carries a unique constellation that complements its function. Many tRNA...
8.
Coon S, Li T, Iben J, Mattijssen S, Maraia R
Methods Enzymol
. 2021 Jun;
655:119-137.
PMID: 34183118
Polyadenylation of the 3' end of mRNAs is an important mechanism for regulating their stability and translation. We developed a nucleotide-resolution, transcriptome-wide, single-molecule SM-PAT-Seq method to accurately measure the polyA...
9.
Mattijssen S, Kozlov G, Fonseca B, Gehring K, Maraia R
RNA Biol
. 2021 Feb;
18(2):259-274.
PMID: 33522422
La-related proteins (LARPs) share a La motif (LaM) followed by an RNA recognition motif (RRM). Together these are termed the La-module that, in the prototypical nuclear La protein and LARP7,...
10.
Mattijssen S, Kozlov G, Gaidamakov S, Ranjan A, Fonseca B, Gehring K, et al.
RNA Biol
. 2020 Dec;
18(2):275-289.
PMID: 33292040
The protein domain arrangement known as the La-module, comprised of a La motif (LaM) followed by a linker and RNA recognition motif (RRM), is found in seven La-related proteins: LARP1,...