Sandra Guns
Overview
Explore the profile of Sandra Guns including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
100
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Recent Articles
1.
Paudel A, Worku Z, Meeus J, Guns S, Van den Mooter G
Int J Pharm
. 2012 Jul;
453(1):253-84.
PMID: 22820134
Spray drying is an efficient technology for solid dispersion manufacturing since it allows extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to solid API-carrier particles. Solvent...
2.
Guns S, Mathot V, Martens J, Van den Mooter G
Eur J Pharm Biopharm
. 2012 Apr;
81(3):674-82.
PMID: 22521332
Since only limited amount of drug is available in early development stages, the extruder design has evolved towards smaller batch sizes, with a more simple design. An in dept study...
3.
Guns S, Dereymaker A, Kayaert P, Mathot V, Martens J, Van den Mooter G
Pharm Res
. 2010 Nov;
28(3):673-82.
PMID: 21104299
Purpose: To investigate the effect of the manufacturing method (spray-drying or hot-melt extrusion) on the kinetic miscibility of miconazole and the graft copolymer poly(ethyleneglycol-g-vinylalcohol). The effect of heat pre-treatment of...
4.
Guns S, Kayaert P, Martens J, Van Humbeeck J, Mathot V, Pijpers T, et al.
Eur J Pharm Biopharm
. 2009 Sep;
74(2):239-47.
PMID: 19782134
In order to fully exploit the graft copolymer poly(ethyleneglycol-g-vinylalcohol) (EG/VA) in the formulation of solid dispersions, a characterization of its phase behavior before, during and after spray-drying and hot-melt extrusion...