Sandra A Jablonski
Overview
Explore the profile of Sandra A Jablonski including associated specialties, affiliations and a list of published articles.
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24
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1292
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Recent Articles
1.
Malchiodi Z, Suter R, Deshpande A, Peran I, Harris B, Duttargi A, et al.
bioRxiv
. 2024 Jun;
PMID: 38853982
Background: Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. PDAC's poor prognosis and resistance to immunotherapy are attributed in part to its dense, fibrotic tumor microenvironment...
2.
Zahavi D, Erbe R, Zhang Y, Guo T, Malchiodi Z, Maynard R, et al.
Cancer Biol Ther
. 2023 Oct;
24(1):2269637.
PMID: 37878417
Targeted monoclonal antibody therapy has emerged as a powerful therapeutic strategy for cancer. However, only a minority of patients have durable responses and the development of resistance remains a major...
3.
Fitzgerald A, Wang S, Agarwal V, Marcisak E, Zuo A, Jablonski S, et al.
J Immunother Cancer
. 2021 Nov;
9(11).
PMID: 34737215
Background: Pancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer death in the USA by 2030. Immune checkpoint inhibitors fail to control most PDAC tumors...
4.
Ajina R, Malchiodi Z, Fitzgerald A, Zuo A, Wang S, Moussa M, et al.
Cancer Immunol Res
. 2021 Jan;
9(4):386-400.
PMID: 33509790
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the United States. Pancreatic tumors are minimally infiltrated by T cells and are largely refractory to immunotherapy....
5.
Zhang Y, Nasto R, Jablonski S, Serebriiskii I, Surana R, Murray J, et al.
Methods Enzymol
. 2020 Mar;
636:299-322.
PMID: 32178823
We have used RNA interference (RNAi) screening technology to reveal unknown components of biological signaling pathways including survival mechanisms of estrogen-independent breast cancer cell growth and cancer cell resistance to...
6.
Ajina R, Zamalin D, Zuo A, Moussa M, Catalfamo M, Jablonski S, et al.
Oncoimmunology
. 2019 May;
8(5):e1577127.
PMID: 31069138
The CRISPR/Cas9 system has recently emerged as a highly efficient modality in genetic engineering and has been widely considered for various therapeutic applications. However, since the effector protein, SpCas9, has...
7.
Sherman T, Kagohara L, Cao R, Cheng R, Satriano M, Considine M, et al.
PLoS Comput Biol
. 2019 Apr;
14(4):e1006935.
PMID: 31002670
Bioinformatics techniques to analyze time course bulk and single cell omics data are advancing. The absence of a known ground truth of the dynamics of molecular changes challenges benchmarking their...
8.
Aldeghaither D, Zahavi D, Murray J, Fertig E, Graham G, Zhang Y, et al.
Cancer Immunol Res
. 2018 Dec;
7(2):230-243.
PMID: 30563830
Targeted monoclonal antibody therapy is a promising therapeutic strategy for cancer, and antibody-dependent cell-mediated cytotoxicity (ADCC) represents a crucial mechanism underlying these approaches. The majority of patients have limited responses...
9.
Zhang Y, Nasto R, Jablonski S, Serebriiskii I, Surana R, Murray J, et al.
Bio Protoc
. 2017 Dec;
7(15).
PMID: 29250574
RNAi screening technology has revealed unknown determinants of various biological signaling pathways in biomedical studies. This protocol provided detailed information about how to use RNAi screening to identify proliferation determinants...
10.
Smith J, Wang S, Nadella S, Jablonski S, Weiner L
Cancer Immunol Immunother
. 2017 Oct;
67(2):195-207.
PMID: 29043413
Advanced pancreatic ductal adenocarcinoma (PDAC) has typically been resistant to chemotherapy and immunotherapy; therefore, novel strategies are needed to enhance therapeutic response. Cholecystokinin (CCK) has been shown to stimulate growth...