Sander R Piersma
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Explore the profile of Sander R Piersma including associated specialties, affiliations and a list of published articles.
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144
Citations
3456
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Recent Articles
1.
Stoof J, Kalmoua Z, Sobota A, Brakenhoff R, Stigter M, Pham T, et al.
Sci Rep
. 2025 Jan;
15(1):2334.
PMID: 39824909
Bladder cancer often recurs, necessitating innovative treatments to reduce recurrence. We investigated non-thermal plasma's potential as a novel anti-cancer therapy, focusing on plasma-activated solution (PAS), created by exposing saline to...
2.
Nollet E, Algul S, Goebel M, Schlossarek S, van der Wel N, Jans J, et al.
J Mol Cell Cardiol Plus
. 2025 Jan;
6():100050.
PMID: 39802622
Background And Aim: Phenotypic expression of hypertrophic cardiomyopathy (HCM) and disease course are associated with unfavorable metabolic health. We investigated if Western diet (WD) feeding is sufficient to trigger cardiac...
3.
Cornelissen F, He Z, Ciputra E, de Haas R, Beumer-Chuwonpad A, Noske D, et al.
Mol Oncol
. 2024 Oct;
19(3):716-740.
PMID: 39417309
Glioblastoma (GB), the most common and aggressive brain tumor, demonstrates intrinsic resistance to current therapies, resulting in poor clinical outcomes. Cancer progression can be partially attributed to the deregulation of...
4.
Podieh F, Overboom M, Knol J, Piersma S, Goeij-de Haas R, Pham T, et al.
Cells
. 2024 Oct;
13(19.
PMID: 39404373
Cell-cell adhesion in endothelial monolayers is tightly controlled and crucial for vascular integrity. Recently, we reported on the importance of fast protein turnover for maintenance of endothelial barrier function. Specifically,...
5.
Rombouts K, van Merrienboer T, Henneman A, Knol J, Pham T, Piersma S, et al.
Arterioscler Thromb Vasc Biol
. 2024 Aug;
44(10):2226-2243.
PMID: 39206541
Background: Abdominal aortic aneurysm (AAA) is characterized by weakening and dilatation of the aortic wall in the abdomen. The aim of this study was to gain insight into cell-specific mechanisms...
6.
Lopez-Cerda M, Lorenzo-Sanz L, da Silva-Diz V, Llop S, Penin R, Bermejo J, et al.
J Exp Clin Cancer Res
. 2024 Jul;
43(1):211.
PMID: 39075581
Background: Early cutaneous squamous cell carcinomas (cSCCs) generally show epithelial differentiation features and good prognosis, whereas advanced cSCCs present mesenchymal traits associated with tumor relapse, metastasis, and poor survival. Currently,...
7.
Suarez-Martinez E, Piersma S, Pham T, Bijnsdorp I, Jimenez C, Carnero A
J Exp Clin Cancer Res
. 2024 May;
43(1):150.
PMID: 38807192
Background: Ovarian cancer has a high mortality rate mainly due to its resistance to currently used therapies. This resistance has been associated with the presence of cancer stem cells (CSCs),...
8.
Navarro-Carrasco E, Monte-Serrano E, Campos-Diaz A, Rolfs F, de Goeij-de Haas R, Pham T, et al.
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38732093
The chromatin organization and its dynamic remodeling determine its accessibility and sensitivity to DNA damage oxidative stress, the main source of endogenous DNA damage. We studied the role of the...
9.
Valles-Marti A, de Goeij-de Haas R, Henneman A, Piersma S, Pham T, Knol J, et al.
Mol Oncol
. 2024 Apr;
18(8):2020-2041.
PMID: 38650175
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a limited number of known driver mutations but considerable cancer cell heterogeneity. Phosphoproteomics provides a direct read-out of aberrant signaling and...
10.
Navarro-Carrasco E, Campos-Diaz A, Monte-Serrano E, Rolfs F, de Goeij-de Haas R, Pham T, et al.
Chem Biol Interact
. 2024 Feb;
391:110908.
PMID: 38367682
Dynamic chromatin remodeling requires regulatory mechanisms for its adaptation to different nuclear function, which are likely to be mediated by signaling proteins. In this context, VRK1 is a nuclear Ser-Thr...