Sander H Diks
Overview
Explore the profile of Sander H Diks including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
549
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Recent Articles
1.
Zomerman W, Plasschaert S, Diks S, Lourens H, Boer T, Hoving E, et al.
PLoS One
. 2015 Oct;
10(10):e0141381.
PMID: 26496080
Recent clinical trials investigating receptor tyrosine kinase (RTK) inhibitors showed a limited clinical response in medulloblastoma. The present study investigated the role of micro-environmental growth factors expressed in the brain,...
2.
van der Sligte N, Scherpen F, Meeuwsen-de Boer T, Lourens H, Ter Elst A, Diks S, et al.
Proteomics
. 2014 Nov;
15(7):1245-54.
PMID: 25422122
Still about 20% of patients with acute lymphoblastic leukemia (ALL) struggle with relapse, despite intensive chemotherapy. We and others have shown that kinase activity profiling is able to give more...
3.
Queiroz K, Milani R, Ruela-de-Sousa R, Fuhler G, Justo G, Zambuzzi W, et al.
PLoS One
. 2012 Oct;
7(10):e45362.
PMID: 23071514
It is now generally recognised that different modes of programmed cell death (PCD) are intimately linked to the cancerous process. However, the mechanism of PCD involved in cancer chemoprevention is...
4.
Sikkema A, den Dunnen W, Hulleman E, van Vuurden D, Garcia-Manero G, Yang H, et al.
Neuro Oncol
. 2012 Jun;
14(9):1125-35.
PMID: 22723427
Eph/ephrin signaling has been implicated in various types of key cancer-enhancing processes, like migration, proliferation, and angiogenesis. In medulloblastoma, invading tumor cells characteristically lead to early recurrence and a decreased...
5.
Tee J, Sartori da Silva M, Rygiel A, Muncan V, Bink R, van den Brink G, et al.
Stem Cells Dev
. 2012 Apr;
21(17):3091-103.
PMID: 22512762
The specific molecular determinants that govern progenitor expansion and final compartment size in the myogenic lineage, either during gestation or during regenerative myogenesis, remain largely obscure. Recently, we retrieved d-asb11...
6.
Hazen A, Diks S, Wahle J, Fuhler G, Peppelenbosch M, Kerr W
J Proteome Res
. 2011 Jun;
10(8):3542-50.
PMID: 21648952
The changes in signal transduction associated with the acquisition of specific cell fates remain poorly understood. We performed massive parallel assessment of kinase signatures of the radiations of the hematopoietic...
7.
Sikkema A, den Dunnen W, Diks S, Peppelenbosch M, de Bont E
Crit Rev Oncol Hematol
. 2011 Jun;
82(2):171-86.
PMID: 21641230
In cancer, genetic and epigenetic alterations ultimately culminate in discordant activation of signal transduction pathways driving the malignant process. Pharmacological or biological inhibition of such pathways holds significant promise with...
8.
Hoogendijk A, Diks S, van der Poll T, Peppelenbosch M, Wieland C
PLoS One
. 2011 Apr;
6(4):e18519.
PMID: 21483672
Background: Pneumonia represents a major health burden. Previous work demonstrated that although the induction of inflammation is important for adequate host defense against pneumonia, an inability to regulate the host's...
9.
Bralten L, Kloosterhof N, Balvers R, Sacchetti A, Lapre L, Lamfers M, et al.
Ann Neurol
. 2011 Mar;
69(3):455-63.
PMID: 21446021
Objective: A high percentage of grade II and III gliomas have mutations in the gene encoding isocitrate dehydrogenase (IDH1). This mutation is always a heterozygous point mutation that affects the...
10.
Hoogendijk A, Diks S, Peppelenbosch M, van der Poll T, Wieland C
Mol Med
. 2011 Mar;
17(7-8):741-7.
PMID: 21424109
Pneumonia is a severe disease with high morbidity and mortality. A major causative pathogen is the Gram-negative bacterium Klebsiella (K.) pneumoniae. Kinases play an integral role in the transduction of...