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Sandeep P Bahekar

Explore the profile of Sandeep P Bahekar including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 29
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Recent Articles
1.
Bhoj P, Bahekar S, Chowdhary S, Togre N, Amdare N, Jena L, et al.
Biomedicines . 2023 Mar; 11(3). PMID: 36979702
A series of Michael adducts of malononitrile and sulfonamide chalcones were synthesized, characterized, and evaluated for their antifilarial activity. Out of 14 compounds, N-(4-(4,4-dicyano-3-p-tolylbutanoyl)phenyl)benzenesulfonamide showed favorable drug-likeness properties with marked...
2.
Bhoj P, Rao S, Bahekar S, Agrawal N, Togre N, Sharma R, et al.
Parasitol Res . 2019 Dec; 119(1):165-175. PMID: 31807868
A novel library of synthetic piperidine derivatives was used to screen against human lymphatic filarial parasite Brugia malayi. Piperidine has earlier been reported to have effect against parasites including rodent...
3.
Manupati K, Debnath S, Goswami K, Bhoj P, Chandak H, Bahekar S, et al.
FEBS J . 2019 Mar; 286(11):2167-2192. PMID: 30873742
Glutathione S-transferase omega 1 (GSTO1) contributes to the inactivation of a wide range of drug compounds via conjugation to glutathione during phase reactions. Chemotherapy-induced GSTO1 expression in breast cancer cells...
4.
Bahekar S, Hande S, Agrawal N, Chandak H, Bhoj P, Goswami K, et al.
Eur J Med Chem . 2016 Sep; 124:262-269. PMID: 27592395
Keeping in mind the immense biological potential of chalcones and sulfonamide scaffolds, a library of sulfonamide chalcones has been synthesized and evaluated for in vitro antifilarial assay against human lymphatic...