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Sampath Prahalad

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Articles 122
Citations 2689
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Recent Articles
11.
Wang Q, Martinez-Bonet M, Kim T, Sparks J, Ishigaki K, Chen X, et al.
Cell Genom . 2023 Nov; 3(11):100420. PMID: 38020975
was among the first loci shown to confer risk for inflammatory arthritis in the absence of an associated coding variant, but its genetic mechanism remains undefined. Using Immunochip data from...
12.
Kohli A, Hersh A, Ponder L, Chan L, Rouster-Stevens K, Tebo A, et al.
Pediatr Rheumatol Online J . 2023 Oct; 21(1):110. PMID: 37798643
Background: The prevalence of Celiac Disease (CD) in Juvenile Idiopathic Arthritis (JIA) has been reported to be 0.1-7% in various small studies. As a result of the limited number of...
13.
Shim J, Park S, Venkateswaran S, Kumar D, Prince C, Parihar V, et al.
Blood . 2023 Aug; 142(23):1972-1984. PMID: 37624902
Hemophagocytic lymphohistiocytosis (HLH) is characterized by hyperinflammation and multiorgan dysfunction. Infections, including the reactivation of viruses, contribute to significant disease mortality in HLH. Although T-cell and natural killer cell-driven immune...
14.
Nguyen T, Kumar D, Prince C, Martini D, Grunwell J, Lawrence T, et al.
J Allergy Clin Immunol . 2023 Jul; 153(1):309-319. PMID: 37517575
Background: Quantifying T-cell activation is essential for the diagnosis and evaluation of treatment response in various hyperinflammatory and immune regulatory disorders, including hemophagocytic lymphohistiocytosis. Plasma soluble IL-2 receptor (sIL-2R) is...
15.
Nelson M, Manos C, Flanagan E, Prahalad S
Ther Adv Vaccines Immunother . 2023 Jun; 11:25151355231181242. PMID: 37362155
Childhood-onset systemic lupus erythematosus (cSLE) is an autoimmune disease associated with significant morbidity and mortality. Rituximab is a B-cell depleting therapy utilized in the treatment of SLE. In adults, rituximab...
16.
Goossens Q, Locsin M, Gharehbaghi S, Brito P, Moise E, Ponder L, et al.
Pediatr Rheumatol Online J . 2023 Jun; 21(1):59. PMID: 37340311
Background: Joint acoustic emissions from knees have been evaluated as a convenient, non-invasive digital biomarker of inflammatory knee involvement in a small cohort of children with Juvenile Idiopathic Arthritis (JIA)....
17.
Villacis-Nunez D, West Z, Khan A, Rodriguez 3rd F, Shane A, Rytting H, et al.
J Investig Med High Impact Case Rep . 2023 Apr; 11:23247096231166672. PMID: 37032536
We present an adolescent male with a single intracardiac mass and pulmonary emboli, complicated by peripheral venous thrombosis and subsequent development of pulmonary pseudoaneurysms, leading to diagnosis of Hughes-Stovin syndrome....
18.
Imbach K, Treadway N, Prahalad V, Kosters A, Arafat D, Duan M, et al.
Pediatr Rheumatol Online J . 2023 Feb; 21(1):17. PMID: 36793127
Background: Juvenile Idiopathic Arthritis (JIA) is an autoimmune disease with a heterogenous clinical presentation and unpredictable response to available therapies. This personalized transcriptomics study sought proof-of-concept for single-cell RNA sequencing...
19.
Nelson M, Chandrakasan S, Ponder L, Sanz I, Goldberg B, Ogbu E, et al.
Children (Basel) . 2022 Dec; 9(12). PMID: 36553310
Introduction: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that is associated with significant morbidity and mortality. SLE disproportionately affects women and minorities. Childhood-onset SLE (cSLE) in particular tends...
20.
Vega-Fernandez P, Oberle E, Henrickson M, Huggins J, Prahalad S, Cassedy A, et al.
Arthritis Care Res (Hoboken) . 2022 Dec; 75(8):1815-1820. PMID: 36530040
Objective: To determine the frequency of subclinical synovitis on musculoskeletal ultrasonography (MSUS) in juvenile idiopathic arthritis (JIA) and correlate patient- and provider-reported outcome measures with MSUS synovitis. Method: JIA patients...