Samir Merabet
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Explore the profile of Samir Merabet including associated specialties, affiliations and a list of published articles.
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47
Citations
625
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Recent Articles
1.
Curt J, Martin P, Foronda D, Hudry B, Kannan R, Shetty S, et al.
PLoS Genet
. 2025 Jan;
21(1):e1011355.
PMID: 39804927
Hox proteins, a sub-group of the homeodomain (HD) transcription factor family, provide positional information for axial patterning in development and evolution. Hox protein functional specificity is reached, at least in...
2.
Vanderperre S, Duffraisse M, Place C, Merabet S
Methods Mol Biol
. 2025 Jan;
2889:39-51.
PMID: 39745604
Bimolecular Fluorescence Complementation (BiFC) is a powerful molecular imaging method used to visualize protein-protein interactions (PPIs) in living cells or organisms. BiFC is based on the reassociation of hemi-fragments of...
3.
Virard F, Giraud S, Bonnet M, Magadoux L, Martin L, Pham T, et al.
Nat Commun
. 2024 Aug;
15(1):7037.
PMID: 39147750
The quest for targeted therapies is critical in the battle against cancer. The RAS/MAP kinase pathway is frequently implicated in neoplasia, with ERK playing a crucial role as the most...
4.
Vanderperre S, Merabet S
Cells
. 2024 Apr;
13(7.
PMID: 38607052
Transcription factors (TFs) regulate gene expression by recognizing specific target enhancers in the genome. The DNA-binding and regulatory activity of TFs depend on the presence of additional protein partners, leading...
5.
Khan S, Pradhan S, Giraud G, Bleicher F, Paul R, Merabet S, et al.
J Mol Evol
. 2023 Jun;
91(5):616-627.
PMID: 37341745
Hox genes encode Homeodomain-containing transcription factors, which specify segmental identities along the anterior-posterior axis. Functional changes in Hox genes have been directly implicated in the evolution of body plans across...
6.
Jia Y, Reboulet J, Gillet B, Hughes S, Forcet C, Tribollet V, et al.
Cells
. 2023 Jan;
12(1).
PMID: 36611993
Biological pathways rely on the formation of intricate protein interaction networks called interactomes. Getting a comprehensive map of interactomes implies the development of tools that allow one to capture transient...
7.
Merabet S, Carnesecchi J
Semin Cell Dev Biol
. 2022 Dec;
152-153:70-75.
PMID: 36481343
Hox genes encode for evolutionary conserved transcription factors that have long fascinated biologists since the observation of the first homeotic transformations in flies. Hox genes are developmental architects that instruct...
8.
Delage L, Lambert M, Bardel E, Kundlacz C, Chartoire D, Conchon A, et al.
Blood
. 2022 Nov;
141(10):1209-1220.
PMID: 36375119
Understanding the functional role of mutated genes in cancer is required to translate the findings of cancer genomics into therapeutic improvement. BTG1 is recurrently mutated in the MCD/C5 subtype of...
9.
Merabet S
J Dev Biol
. 2022 Aug;
10(3).
PMID: 35997398
In this Special Issue on "Hox genes in development: new paradigms", we present a compilation of articles and reviews tackling various aspects of the Hox biology field [...].
10.
Boumpas P, Merabet S, Carnesecchi J
Wiley Interdiscip Rev RNA
. 2022 Jul;
14(2):e1752.
PMID: 35899407
Transcription factors (TFs) are present in all life forms and conserved across great evolutionary distances in eukaryotes. From yeast to complex multicellular organisms, they are pivotal players of cell fate...