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Sami A Al-Hussain

Explore the profile of Sami A Al-Hussain including associated specialties, affiliations and a list of published articles. Areas
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Articles 88
Citations 240
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Recent Articles
1.
Masand V, Patil M, Al-Hussain S, Samad A, Rastija V, Jawarkar R, et al.
Chem Biol Drug Des . 2025 Feb; 105(2):e70060. PMID: 39912316
Despite advancements in molecular design rules and understanding biochemical processes, the field of drug design and discovery seeks to minimize the number and duration of synthesis-testing cycles to convert lead...
2.
Abu-Hashem A, Al-Hussain S
Pharmaceuticals (Basel) . 2025 Jan; 17(12. PMID: 39770474
Background: Recently, pyrido[2,3-] pyrimidine, triazolopyrimidine, thiazolopyrimidine, quinoline, and pyrazole derivatives have gained attention due to their diverse biological activities, including antimicrobial, antioxidant, antitubercular, antitumor, anti-inflammatory, and antiviral effects. Objective: The...
3.
Jawarkar R, Mali S, Deshmukh P, Ingle R, Al-Hussain S, Al-Mutairi A, et al.
J Mol Graph Model . 2024 Dec; 135():108915. PMID: 39729811
The work being presented now combines severe gradient boosting with Shapley values, a thriving merger within the field of explainable artificial intelligence. We also use a genetic algorithm to analyse...
4.
Khandia R, Gurjar P, Priyanka , Romashchenko V, Al-Hussain S, Zaki M
Int J Surg . 2024 Dec; 110(10):6367-6381. PMID: 39705668
Neurodegeneration refers to the gradual loss of neurons and extensive changes in glial cells like tau inclusions in astrocytes and oligodendrocytes, α-synuclein inclusions in oligodendrocytes and SOD1 aggregates in astrocytes...
5.
Zaheen A, Rajkhowa S, Al-Hussain S, Zaki M
J Cell Mol Med . 2024 Dec; 28(23):e70158. PMID: 39629503
Rungia pectinata L. is an ethnomedicinal herb belonging to the Acanthaceae family and it presents a promising avenue for medicinal exploration, deeply rooted in traditional practices. Earlier research has demonstrated...
6.
Al-Humaidi J, Albedair L, Maliwal D, Zaki M, Al-Hussain S, Pissurlenkar R, et al.
Chem Biodivers . 2024 Oct; 22(2):e202401766. PMID: 39440719
α-Glucosidase inhibitors are critical for diabetes management, with pyrazoles and thiazoles emerging as effective options. This research highlights curcumin-based pyrazole-thiazole hybrids as potential inhibitors, synthesizing derivatives and evaluating their inhibitory...
7.
Irfan A, Zahoor A, Boulaamane Y, Javed S, Hameed H, Maurady A, et al.
Front Chem . 2024 Oct; 12:1449165. PMID: 39439933
Monoamine oxidase B (MAO-B) plays a pivotal role in the deamination process of monoamines, encompassing crucial neurotransmitters like dopamine and norepinephrine. The heightened interest in MAO-B inhibitors emerged after the...
8.
Akhtar M, Jutt D, Aslam S, Nawaz R, Irshad M, Khan M, et al.
Sci Rep . 2024 Oct; 14(1):23094. PMID: 39367070
Graphene-based nanomaterials have been proved to be robust sorbents for efficient removal of environmental contaminants including arsenic (As). Biobased graphene oxide (bGO-P) derived from sugarcane bagasse via pyrolysis, GO-C via...
9.
Rajkhowa S, Hussain S, Agarwal M, Zaheen A, Al-Hussain S, Zaki M
Pharmaceutics . 2024 Sep; 16(9). PMID: 39339197
The increase in antibiotic-resistant bacteria presents a significant risk to worldwide public health, emphasizing the necessity of novel approaches to address infections. Quorum sensing, an essential method of communication among...
10.
Shah S, Chaple D, Masand V, Jawarkar R, Chaudhari S, Abiramasundari A, et al.
Sci Rep . 2024 Sep; 14(1):20740. PMID: 39237650
No abstract available.