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Sameer Mohammad

Explore the profile of Sameer Mohammad including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 561
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Recent Articles
21.
Bouchama A, Aziz M, Al Mahri S, Gabere M, Dlamy M, Mohammad S, et al.
Sci Rep . 2017 Aug; 7(1):9429. PMID: 28842615
The molecular mechanisms by which individuals subjected to environmental heat stress either recover or develop heat-related complications are not well understood. We analysed the changes in blood mononuclear gene expression...
22.
Alhawiti N, Al Mahri S, Aziz M, Malik S, Mohammad S
Curr Drug Targets . 2017 Feb; 18(9):1095-1103. PMID: 28137209
Summary: Consequently, targeting TXNIP is thought to offer novel therapeutic opportunity and TXNIP inhibitors have the potential to become a powerful therapeutic tool for the treatment of diabetes mellitus. Here...
23.
Mohammad S
Curr Drug Targets . 2015 Dec; 17(11):1292-300. PMID: 26648068
Apart from functioning as an energy source and important structural components of biological membranes, Free Fatty acids (FFAs) play a key role in the regulation of metabolic homeostasis. FFAs activate...
24.
Mohammad S
Curr Drug Targets . 2015 Apr; 16(7):771-5. PMID: 25850624
Besides being an important source of fuel and structural components of biological membranes, free fatty acids (FFAs) are known to display a wide variety of roles that include modulation of...
25.
Mohammad S, Patel R, Bruno J, Panhwar M, Wen J, McGraw T
Mol Cell Biol . 2014 Jul; 34(19):3618-29. PMID: 25047836
Glucose-dependent insulinotropic polypeptide (GIP), an incretin hormone secreted from gastrointestinal K cells in response to food intake, has an important role in the control of whole-body metabolism. GIP signals through...
26.
McDaniel F, Molden B, Mohammad S, Baldini G, McPike L, Narducci P, et al.
J Biol Chem . 2012 May; 287(26):21873-90. PMID: 22544740
Melanocortin-4 receptor (MC4R) is a G-protein-coupled receptor expressed in the hypothalamus where it controls feeding behavior. MC4R cycles constitutively and is internalized at the same rate in the presence or...
27.
Mohammad S, Ramos L, Buck J, Levin L, Rubino F, McGraw T
J Biol Chem . 2011 Oct; 286(50):43062-70. PMID: 22027830
Gastric inhibitory peptide (GIP) is an incretin hormone secreted in response to food intake. The best known function of GIP is to enhance glucose-dependent insulin secretion from pancreatic β-cells. Extra-pancreatic...
28.
Granell S, Mohammad S, Ramanagoudr-Bhojappa R, Baldini G
Mol Endocrinol . 2010 Jul; 24(9):1805-21. PMID: 20631012
Melanocortin-4 receptor (MC4R) is a G protein-coupled receptor expressed in the brain where it controls food intake. Many obesity-linked MC4R variants are poorly expressed at the plasma membrane and are...
29.
Granell S, Baldini G, Mohammad S, Nicolin V, Narducci P, Storrie B, et al.
Mol Biol Cell . 2007 Nov; 19(2):572-86. PMID: 18045994
A variant alpha1-antitrypsin with E342K mutation has a high tendency to form intracellular polymers, and it is associated with liver disease. In the hepatocytes of individuals carrying the mutation, alpha1-antitrypsin...
30.
Mohammad S, Baldini G, Granell S, Narducci P, Martelli A, Baldini G
J Biol Chem . 2006 Dec; 282(7):4963-4974. PMID: 17166828
Melanocortin-4 receptor (MC4R) is a G protein-coupled receptor (GPCR) that binds alpha-melanocyte-stimulating hormone (alpha-MSH) and has a central role in the regulation of appetite and energy expenditure. Most GPCRs are...