Samar Fadl
Overview
Explore the profile of Samar Fadl including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
102
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0
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Recent Articles
1.
Ferreira J, Villanueva A, Al Adem K, Fadl S, Alzyoud L, Ghattas M, et al.
J Biol Chem
. 2024 Sep;
300(11):107821.
PMID: 39342997
Coronaviruses such as SARS-CoV-2 encode a conserved papain-like protease (PLpro) that is crucial for viral replication and immune evasion, making it a prime target for antiviral drug development. In this...
2.
Ferreira J, Fadl S, Cardoso T, Andrade B, Melo T, Silva E, et al.
Biosci Rep
. 2024 Jul;
44(8).
PMID: 39045772
SARS-CoV-2 was first discovered in 2019 and has disseminated throughout the globe to pandemic levels, imposing significant health and economic burdens. Although vaccines against SARS-CoV-2 have been developed, their long-term...
3.
Al Adem K, Ferreira J, Villanueva A, Fadl S, El-Sadaany F, Masmoudi I, et al.
Biosci Rep
. 2024 Jul;
44(8).
PMID: 39036877
Coronaviruses constitute a significant threat to the human population. Severe acute respiratory syndrome coronavirus-2, SARS-CoV-2, is a highly pathogenic human coronavirus that has caused the coronavirus disease 2019 (COVID-19) pandemic....
4.
Ferreira J, Villanueva A, Fadl S, Al Adem K, Cinviz Z, Nedyalkova L, et al.
J Biol Chem
. 2024 Jul;
300(8):107538.
PMID: 38971308
Excessive fructose consumption is a primary contributor to the global surges in obesity, cancer, and metabolic syndrome. Fructolysis is not robustly regulated and is initiated by ketohexokinase (KHK). In this...
5.
Al Adem K, Ferreira J, Fadl S, Mustafa M, Rabeh W
Biochem J
. 2023 May;
PMID: 37254750
The main protease of SARS-CoV-2, 3-chymotrypsin-like protease (3CLpro), is a prominent target for antiviral development due to its essential role in the viral life cycle. Research has largely focused on...
6.
Al Adem K, Ferreira J, Fadl S, Rabeh W
J Biol Chem
. 2022 Dec;
299(2):102790.
PMID: 36509143
3-Chymotrypsin-like protease (3CLpro) is a promising drug target for coronavirus disease 2019 and related coronavirus diseases because of the essential role of this protease in processing viral polyproteins after infection....
7.
Ferreira J, Fadl S, Rabeh W
J Biol Chem
. 2022 May;
298(6):102023.
PMID: 35568197
3C-like protease (3CLpro) processes and liberates functional viral proteins essential for the maturation and infectivity of severe acute respiratory syndrome coronavirus 2, the virus responsible for COVID-19. It has been...
8.
Deliorman M, Janahi F, Sukumar P, Glia A, Alnemari R, Fadl S, et al.
Microsyst Nanoeng
. 2021 Sep;
6:20.
PMID: 34567635
Circulating tumor cells (CTCs) carried by the patient's bloodstream are known to lead to the metastatic spread of cancer. It is becoming increasingly clear that an understanding of the nanomechanical...
9.
Ferreira J, Fadl S, Ilter M, Pekel H, Rezgui R, Sensoy O, et al.
FASEB J
. 2021 Jul;
35(8):e21774.
PMID: 34324734
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19), one of the most challenging global pandemics of the modern era. Potential treatment strategies against COVID-19...
10.
Ferreira J, Fadl S, Villanueva A, Rabeh W
Front Chem
. 2021 Jul;
9:692168.
PMID: 34249864
Coronaviruses are responsible for multiple pandemics and millions of deaths globally, including the current pandemic of coronavirus disease 2019 (COVID-19). Development of antivirals against coronaviruses, including the severe acute respiratory...