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Sam O Shepherd

Explore the profile of Sam O Shepherd including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 44
Citations 727
Followers 0
Related Specialties
Physiology
Endocrinology
Orthopedics
Top 10 Co-Authors
Anton J M Wagenmakers
Juliette A Strauss
Matthew Cocks
James P Morton
Christopher S Shaw
Matt Cocks
Adam P. Sharples
Graeme L Close
Kelly M Hammond
Sam N Scott
Published In
J Physiol
J Clin Endocrinol Metab
Med Sci Sports Exerc
Front Physiol
PLoS One
Affiliations
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Recent Articles
1.
Effect of self-paced sprint interval training and low-volume HIIT on cardiorespiratory fitness: the role of heart rate and power output
Hesketh K, Shepherd S, Wagenmakers A, Cocks M, Strauss J
Front Physiol . 2025 Feb; 16:1484722. PMID: 39973903
Aim: The primary aim was to assess the efficacy of self-paced sprint interval training (SIT) with low-volume high-intensity interval training (LV-HIIT) when performed without encouragement on improving cardiorespiratory fitness (CRF)....
2.
A free-living, walking-based, exercise programme, with exercise timed relative to breakfast, to improve metabolic health in people living with overweight and obesity: A feasibility study
Barrett J, Crozier A, Cuthbertson D, Strauss J, Wagenmakers A, Shepherd S
PLoS One . 2024 Nov; 19(11):e0307582. PMID: 39570874
Optimising the timing of food intake relative to exercise may maximise the effectiveness of free-living exercise programmes on improvements in glycaemic control and cardio-metabolic health. This study aimed to assess...
3.
Polygenic mechanisms underpinning the response to exercise-induced muscle damage in humans: In vivo and in vitro evidence
Baumert P, Cocks M, Strauss J, Shepherd S, Drust B, Lake M, et al.
J Cell Physiol . 2022 Mar; 237(7):2862-2876. PMID: 35312042
We investigated whether 20 candidate single nucleotide polymorphisms (SNPs) were associated with in vivo exercise-induced muscle damage (EIMD), and with an in vitro skeletal muscle stem cell wound healing assay....
4.
Home-Based HIIT and Traditional MICT Prescriptions Improve Cardiorespiratory Fitness to a Similar Extent Within an Exercise Referral Scheme for At-Risk Individuals
Hesketh K, Jones H, Kinnafick F, Shepherd S, Wagenmakers A, Strauss J, et al.
Front Physiol . 2021 Dec; 12:750283. PMID: 34858205
Exercise referral schemes (ERS) are used to promote physical activity within primary care. Traditionally, ERS are conducted in a gym or leisure-center setting, with exercise prescriptions based on moderate-intensity continuous...
5.
Evidence-based vs. social media based high-intensity interval training protocols: Physiological and perceptual responses
Hesketh K, Church H, Kinnafick F, Shepherd S, Wagenmakers A, Cocks M, et al.
PLoS One . 2021 Sep; 16(9):e0257685. PMID: 34587217
Objective: High intensity interval training (HIIT) is a time-efficient exercise modality to improve cardiorespiratory fitness, and has recently been popularised by social media influencers. However, little is known regarding acute...
6.
Carbohydrate improves exercise capacity but does not affect subcellular lipid droplet morphology, AMPK and p53 signalling in human skeletal muscle
Fell J, Hearris M, Ellis D, Moran J, Jevons E, Owens D, et al.
J Physiol . 2021 Mar; 599(11):2823-2849. PMID: 33772787
Key Points: Muscle glycogen and intramuscular triglycerides (IMTG, stored in lipid droplets) are important energy substrates during prolonged exercise. Exercise-induced changes in lipid droplet (LD) morphology (i.e. LD size and...
7.
The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle
Maasar M, Turner D, Gorski P, Seaborne R, Strauss J, Shepherd S, et al.
Front Physiol . 2021 Mar; 12:619447. PMID: 33679435
The methylome and transcriptome signatures following exercise that are physiologically and metabolically relevant to sporting contexts such as team sports or health prescription scenarios (e.g., high intensity interval training/HIIT) has...
8.
Sit Less and Move More-A Multicomponent Intervention With and Without Height-Adjustable Workstations in Contact Center Call Agents: A Pilot Randomized Controlled Trial
Morris A, Murphy R, Hopkins N, Low D, Healy G, Edwardson C, et al.
J Occup Environ Med . 2020 Oct; 63(1):44-56. PMID: 33122540
Objective: To pilot a multicomponent intervention to sit less and move more, with (SLAMM+) and without (SLAMM) height-adjustable workstations, in contact center call agents. Methods: Agents were individually randomized to...
9.
Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle
Hearris M, Owens D, Strauss J, Shepherd S, Sharples A, Morton J, et al.
Exp Physiol . 2020 Aug; 105(11):1882-1894. PMID: 32862503
New Findings: What is the central question of this study? What is the absolute level of pre-exercise glycogen concentration required to augment the exercise-induced signalling response regulating mitochondrial biogenesis? What...
10.
Diurnal Differences in Human Muscle Isometric Force In Vivo Are Associated with Differential Phosphorylation of Sarcomeric M-Band Proteins
Ab Malik Z, Bowden Davies K, Hall E, Barrett J, Pullinger S, Erskine R, et al.
Proteomes . 2020 Aug; 8(3). PMID: 32859009
We investigated whether diurnal differences in muscle force output are associated with the post-translational state of muscle proteins. Ten physically active men (mean ± SD; age 26.7 ± 3.7 y)...