Sam Mesiano
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Explore the profile of Sam Mesiano including associated specialties, affiliations and a list of published articles.
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75
Citations
1868
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Recent Articles
21.
Hoffman M, Mann L, Won J, Bergh E, Donepudi R, Johnson A, et al.
Am J Perinatol
. 2020 Jan;
37(6):562-569.
PMID: 31891958
Objective: Preterm delivery following fetoscopic laser surgery (FLS) of twin-twin transfusion syndrome (TTTS) is associated with severe perinatal morbidity and mortality. The role of steroid hormones in amniotic fluid (AF)...
22.
Stanfield Z, Amini P, Wang J, Yi L, Tan H, Chance M, et al.
Mol Hum Reprod
. 2019 Jun;
25(7):408-422.
PMID: 31211832
Parturition involves cellular signaling changes driven by the complex interplay between progesterone (P4), inflammation, and the cyclic adenosine monophosphate (cAMP) pathway. To characterize this interplay, we performed comprehensive transcriptomic studies...
23.
Stanfield Z, Lai P, Lei K, Johnson M, Blanks A, Romero R, et al.
Front Genet
. 2019 Jun;
10:515.
PMID: 31191621
[This corrects the article DOI: 10.3389/fgene.2019.00185.].
24.
Stanfield Z, Lai P, Lei K, Johnson M, Blanks A, Romero R, et al.
Front Genet
. 2019 Apr;
10:185.
PMID: 30988671
The process of parturition involves the transformation of the quiescent myometrium (uterine smooth muscle) to the highly contractile laboring state. This is thought to be driven by changes in gene...
25.
Heuerman A, Hollinger T, Menon R, Mesiano S, Yellon S
Reprod Sci
. 2019 Jan;
26(5):690-696.
PMID: 30654718
The prepartum transition from a soft to ripening cervix is an inflammatory process that occurs well before birth when systemic progesterone is near peak concentration. This 2-part study first determined...
26.
Hadley E, Sheller-Miller S, Saade G, Salomon C, Mesiano S, Taylor R, et al.
Am J Obstet Gynecol
. 2018 Aug;
219(5):478.e1-478.e21.
PMID: 30138617
Background: Fetal endocrine signals are generally considered to contribute to the timing of birth and the initiation of labor. Fetal tissues under oxidative stress release inflammatory mediators that lead to...
27.
Amini P, Wilson R, Wang J, Tan H, Yi L, Koeblitz W, et al.
Mol Cell Endocrinol
. 2018 Aug;
479:1-11.
PMID: 30118888
Progesterone (P4) acting through the P4 receptor (PR) isoforms, PR-A and PR-B, promotes uterine quiescence for most of pregnancy, in part, by inhibiting the response of myometrial cells to pro-labor...
28.
Li J, Hong X, Mesiano S, Muglia L, Wang X, Snyder M, et al.
Am J Hum Genet
. 2018 Jun;
103(1):45-57.
PMID: 29937092
The progesterone receptor (PGR) plays a central role in maintaining pregnancy and is significantly associated with medical conditions such as preterm birth that affects 12.6% of all the births in...
29.
Collins G, Mesiano S, DiFeo A
Reprod Sci
. 2018 Jun;
26(5):609-618.
PMID: 29848180
Endometrial cancer (EC) is the most common gynecologic malignancy and is the result of disruption of the balance between estrogen-stimulated growth and progesterone-induced growth modulation. Metformin has been shown to...
30.
Weatherborn M, Mesiano S
Best Pract Res Clin Obstet Gynaecol
. 2018 May;
52:114-125.
PMID: 29724668
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide. The only medicinal therapy currently recommended to prevent PTB is prophylactic progestin therapy in the form of...