Sam H Whiting
Overview
Explore the profile of Sam H Whiting including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
57
Followers
0
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Recent Articles
1.
Yarchoan M, Powderly J, Bastos B, Karasic T, Crysler O, Munster P, et al.
Cancer Res Commun
. 2024 Mar;
4(4):1100-1110.
PMID: 38551394
Purpose: TPST-1120 is a first-in-class oral inhibitor of peroxisome proliferator-activated receptor α (PPARα), a fatty acid ligand-activated transcription factor that regulates genes involved in fatty acid oxidation, angiogenesis, and inflammation,...
2.
Coveler A, Pillarisetty V, Koh W, Zhen D, Park J, King G, et al.
Pancreas
. 2023 Oct;
52(5):e282-e287.
PMID: 37782886
Objectives: Pancreatic ductal adenocarcinoma (PDA) is the third most common cause of cancer death in the United States. Most patients who undergo resection develop recurrence. Standard treatment confers a median...
3.
Meric-Bernstam F, Tannir N, Iliopoulos O, Lee R, Telli M, Fan A, et al.
Clin Cancer Res
. 2022 Feb;
28(8):1540-1548.
PMID: 35140121
Purpose: Dual inhibition of glucose and glutamine metabolism results in synergistic anticancer effects in solid tumor models. Telaglenastat, an investigational, small-molecule, glutaminase inhibitor, exhibits modest single-agent activity in renal cell...
4.
Harding J, Telli M, Munster P, Voss M, Infante J, DeMichele A, et al.
Clin Cancer Res
. 2021 Jul;
27(18):4994-5003.
PMID: 34285061
Purpose: Glutamine is a critical fuel for solid tumors. Interference with glutamine metabolism is deleterious to neoplasia in preclinical models. A phase I study of the oral, first-in-class, glutaminase (GLS)...