Sam Groom
Overview
Explore the profile of Sam Groom including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
21
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0
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Recent Articles
1.
Feetham C, Collabolletta V, Worth A, Shoop R, Groom S, Harding C, et al.
Nat Commun
. 2024 Dec;
15(1):10749.
PMID: 39737892
Growth differentiation factor 15, GDF15, and glucagon-like peptide-1 (GLP-1) analogues act through brainstem neurons that co-localise their receptors, GDNF-family receptor α-like (GFRAL) and GLP1R, to reduce food intake and body...
2.
Ramos-Gonzalez N, Groom S, Sutcliffe K, Bancroft S, Bailey C, Sessions R, et al.
Br J Pharmacol
. 2023 Apr;
180(18):2341-2360.
PMID: 37005796
Background And Purpose: The illicit use of fentanyl-like drugs (fentanyls), which are μ opioid receptor agonists, and the many overdose deaths that result, has become a major problem. Fentanyls are...
3.
Sutcliffe K, Corey R, Alhosan N, Cavallo D, Groom S, Santiago M, et al.
Adv Drug Alcohol Res
. 2022 Aug;
2.
PMID: 35909438
Overdose deaths from fentanyl have reached epidemic proportions in the USA and are increasing worldwide. Fentanyl is a potent opioid agonist that is less well reversed by naloxone than morphine....
4.
Groom S, Blum N, Conibear A, Disney A, Hill R, Husbands S, et al.
Br J Pharmacol
. 2020 Nov;
180(7):943-957.
PMID: 33245558
Background And Purpose: G protein-biased μ opioid receptor agonists have the potential to induce less receptor desensitisation and tolerance than balanced opioids. Here, we investigated if the cyclic endomorphin analogue...