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Sam Duwe

Explore the profile of Sam Duwe including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 232
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Recent Articles
1.
Scheijen E, Veeningen N, Duwe S, Ivanova A, Van Broeckhoven J, Hendrix S, et al.
J Biomed Sci . 2025 Jan; 32(1):12. PMID: 39844195
Background: Deficient DNA repair and excessive DNA damage contribute to neurodegenerative disease. However, the role of DNA damage and repair in spinal cord injury (SCI) is unclear. SCI, a debilitating...
2.
Pancaro A, Szymonik M, Perez Schmidt P, Erol G, Garcia Barrientos A, Polito L, et al.
ACS Appl Mater Interfaces . 2024 May; 16(23):30556-30566. PMID: 38806166
Mannose-binding lectin (MBL) activates the complement system lectin pathway and subsequent inflammatory mechanisms. The incidence and outcome of many human diseases, such as brain ischemia and infections, are associated with...
3.
Garcia-Mendivil L, Perez-Zabalza M, Duwe S, Ordovas L, Pueyo E
STAR Protoc . 2023 Nov; 4(4):102730. PMID: 37980568
The procedures used routinely for collagen and lipofuscin evaluation are, in many cases, qualitative, observer dependent, and disregard spatial distribution. Here, we present a protocol for automatic quantification and spatial...
4.
Hargreaves R, Duwe S, Rozario A, Funston A, Tabor R, Dedecker P, et al.
ACS Bio Med Chem Au . 2023 Jun; 3(3):261-269. PMID: 37363082
Standard optical imaging is diffraction-limited and lacks the resolving power to visualize many of the organelles and proteins found within the cell. The advent of super-resolution techniques overcame this barrier,...
5.
Valenta H, Hugelier S, Duwe S, Lo Gerfo G, Muller M, Dedecker P, et al.
Biophys Rep (N Y) . 2022 Nov; 1(2):100026. PMID: 36425462
Multicolor fluorescence imaging is an excellent method for the simultaneous visualization of multiple structures, although it is limited by the available spectral window. More labels can be measured by distinguishing...
6.
Garcia-Mendivil L, Perez-Zabalza M, Mountris K, Duwe S, Smisdom N, Perez M, et al.
iScience . 2022 Feb; 25(2):103822. PMID: 35198884
Age-related fibrosis in the left ventricle (LV) has been mainly studied in animals by assessing collagen content. Using second-harmonic generation microscopy and image processing, we evaluated amount, aggregation and spatial...
7.
Rozario A, Duwe S, Elliott C, Hargreaves R, Moseley G, Dedecker P, et al.
BMC Biol . 2021 Dec; 19(1):260. PMID: 34895240
Background: The integrity of microtubule filament networks is essential for the roles in diverse cellular functions, and disruption of its structure or dynamics has been explored as a therapeutic approach...
8.
Van Genechten W, Demuyser L, Duwe S, Vandenberg W, Van Dijck P, Dedecker P
mSphere . 2021 Mar; 6(2). PMID: 33731469
Fluorescence microscopy is a standard research tool in many fields, although collecting reliable images can be difficult in systems characterized by low expression levels and/or high background fluorescence. We present...
9.
De Zitter E, Hugelier S, Duwe S, Vandenberg W, Tebo A, Meervelt L, et al.
Angew Chem Int Ed Engl . 2021 Feb; 60(18):10073-10081. PMID: 33543524
Anisotropic environments can drastically alter the spectroscopy and photochemistry of molecules, leading to complex structure-function relationships. We examined this using fluorescent proteins as easy-to-modify model systems. Starting from a single...
10.
Yongabi D, Khorshid M, Gennaro A, Jooken S, Duwe S, Deschaume O, et al.
ACS Appl Mater Interfaces . 2020 Apr; 12(16):18258-18272. PMID: 32223273
Cell-material interactions are crucial for many biomedical applications, including medical implants, tissue engineering, and biosensors. For implants, while the adhesion of eukaryotic host cells is desirable, bacterial adhesion often leads...