Salvatore Loguercio
Overview
Explore the profile of Salvatore Loguercio including associated specialties, affiliations and a list of published articles.
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26
Citations
463
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Recent Articles
1.
Wang Y, Hilsman J, Li C, Morris M, Heider P, Fu S, et al.
medRxiv
. 2025 Feb;
PMID: 39974073
Electronic health record (EHR) data are a rich and invaluable source of real-world clinical information, enabling detailed insights into patient populations, treatment outcomes, and healthcare practices. The availability of large...
2.
Yang C, Fazli L, Loguercio S, Zharkikh I, Aza-Blanc P, Gleave M, et al.
Oncotarget
. 2025 Feb;
16:65-66.
PMID: 39945472
No abstract available.
3.
Sadaei H, Loguercio S, Shafiei Neyestanak M, Torkamani A, Prilutsky D
Pac Symp Biocomput
. 2023 Dec;
29:81-95.
PMID: 38160271
In the intricate landscape of healthcare analytics, effective feature selection is a prerequisite for generating robust predictive models, especially given the common challenges of sample sizes and potential biases. Zoish...
4.
Understanding the host-pathogen evolutionary balance through Gaussian process modeling of SARS-CoV-2
Loguercio S, Calverley B, Wang C, Shak D, Zhao P, Sun S, et al.
Patterns (N Y)
. 2023 Aug;
4(8):100800.
PMID: 37602209
We have developed a machine learning (ML) approach using Gaussian process (GP)-based spatial covariance (SCV) to track the impact of spatial-temporal mutational events driving host-pathogen balance in biology. We show...
5.
Dias R, Evans D, Chen S, Chen K, Loguercio S, Chan L, et al.
Elife
. 2022 Sep;
11.
PMID: 36148981
Genotype imputation is a foundational tool for population genetics. Standard statistical imputation approaches rely on the co-location of large whole-genome sequencing-based reference panels, powerful computing environments, and potentially sensitive genetic...
6.
Tran D, Pottekat A, Lee K, Raghunathan M, Loguercio S, Mir S, et al.
J Clin Endocrinol Metab
. 2022 Aug;
107(11):3100-3110.
PMID: 36017587
Context: Aberrant biosynthesis and secretion of the insulin precursor proinsulin occurs in both type I and type II diabetes. Inflammatory cytokines are implicated in pancreatic islet stress and dysfunction in...
7.
Tran D, Pottekat A, Mir S, Loguercio S, Jang I, Campos A, et al.
Diabetes
. 2020 May;
69(8):1723-1734.
PMID: 32457219
The β-cell protein synthetic machinery is dedicated to the production of mature insulin, which requires the proper folding and trafficking of its precursor, proinsulin. The complete network of proteins that...
8.
Wang C, Scott S, Subramanian K, Loguercio S, Zhao P, Hutt D, et al.
Nat Commun
. 2019 Nov;
10(1):5052.
PMID: 31699992
To understand the impact of epigenetics on human misfolding disease, we apply Gaussian-process regression (GPR) based machine learning (ML) (GPR-ML) through variation spatial profiling (VSP). VSP generates population-based matrices describing...
9.
Kleiman E, Loguercio S, Feeney A
Front Immunol
. 2018 Oct;
9:2074.
PMID: 30271408
To date there has not been a study directly comparing relative Igκ rearrangement frequencies obtained from genomic DNA (gDNA) and cDNA and since each approach has potential biases, this is...
10.
Hutt D, Loguercio S, Roth D, Su A, Balch W
J Biol Chem
. 2018 Jul;
293(35):13477-13495.
PMID: 30006345
Inherited and somatic rare diseases result from >200,000 genetic variants leading to loss- or gain-of-toxic function, often caused by protein misfolding. Many of these misfolded variants fail to properly interact...