Salvador Casares
Overview
Explore the profile of Salvador Casares including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
153
Followers
0
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Recent Articles
1.
Reifs A, Fernandez-Calvo A, Alonso-Lerma B, Schonfelder J, Franco D, Ortega-Munoz M, et al.
J Biol Chem
. 2024 Mar;
300(4):107133.
PMID: 38432632
Protein mechanical stability determines the function of a myriad of proteins, especially proteins from the extracellular matrix. Failure to maintain protein mechanical stability may result in diseases and disorders such...
2.
Hermosilla J, Perez-Robles R, Salmeron-Garcia A, Casares S, Cabeza J, Navas N
J Pharm Biomed Anal
. 2021 Jun;
203:114209.
PMID: 34153938
A range of biopharmaceutical products are used to target Vascular Endothelial Growth Factor (VEGF), including Eylea® (aflibercept, AFL) and Zaltrap® (ziv-aflibercept, ziv-AFL). The first is indicated for ophthalmological diseases such...
3.
Hermosilla J, Perez-Robles R, Salmeron-Garcia A, Casares S, Cabeza J, Bones J, et al.
Sci Rep
. 2020 Feb;
10(1):2675.
PMID: 32060315
Aflibercept (AFL) is an Fc fusion protein used in the treatment of colorectal cancers and different ophthalmological diseases. There are two medicines in which AFL is the active substance: Zaltrap...
4.
Peigneux A, Jabalera Y, Vivas M, Casares S, Azuaga A, Jimenez-Lopez C
Sci Rep
. 2019 Jun;
9(1):8804.
PMID: 31217514
The role of magnetosome associated proteins on the in vitro synthesis of magnetite nanoparticles has gained interest, both to obtain a better understanding of the magnetosome biomineralization process and to...
5.
Hermosilla J, Sanchez-Martin R, Perez-Robles R, Salmeron-Garcia A, Casares S, Cabeza J, et al.
BioDrugs
. 2019 Mar;
33(2):193-205.
PMID: 30875076
Background: There are two products in which infliximab is the active pharmaceutical ingredient. These are Remicade (INF; reference product) and Remsima™/Inflectra™ (CT-P13; infliximab biosimilar). Remsima™/Inflectra™ are bioidentical products. Different recommendations...
6.
Castello F, Paredes J, Ruedas-Rama M, Martin M, Roldan M, Casares S, et al.
Sci Rep
. 2017 Jan;
7:40065.
PMID: 28067252
The self-assembly of proteins into fibrillar structures called amyloid fibrils underlies the onset and symptoms of neurodegenerative diseases, such as Alzheimer's and Parkinson's. However, the molecular basis and mechanism of...
7.
Manssour-Triedo F, Crespillo S, Morel B, Casares S, Mateo P, Notka F, et al.
Biophys J
. 2016 Aug;
111(4):700-709.
PMID: 27558714
The HIV gp41 ectodomain (e-gp41) is an attractive target for the development of vaccines and drugs against HIV because of its crucial role in viral fusion to the host cell....
8.
Castello F, Casares S, Ruedas-Rama M, Orte A
J Phys Chem B
. 2015 Jun;
119(26):8260-7.
PMID: 26039157
The structural and dynamic characterization of the on-pathway intermediates involved in the mechanism of amyloid fibril formation is one of the major remaining biomedical challenges of our time. In addition...
9.
Crespillo S, Camara-Artigas A, Casares S, Morel B, Cobos E, Mateo P, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
111(51):18207-12.
PMID: 25489108
During HIV-1 fusion to the host cell membrane, the N-terminal heptad repeat (NHR) and the C-terminal heptad repeat (CHR) of the envelope subunit gp41 become transiently exposed and accessible to...
10.
Crespillo S, Casares S, Mateo P, Conejero-Lara F
J Biol Chem
. 2013 Dec;
289(2):594-9.
PMID: 24302742
Immunotherapies and vaccines based on the induction of broadly neutralizing monoclonal antibodies (bNAbs) have become outstanding strategies against HIV-1. Diverse bNAbs recognizing different regions of the HIV-1 envelope have been...