Sakunthala C Kudahetti
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Explore the profile of Sakunthala C Kudahetti including associated specialties, affiliations and a list of published articles.
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13
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399
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Recent Articles
1.
The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis
Marzec J, Ross-Adams H, Pirro S, Wang J, Zhu Y, Mao X, et al.
Cancers (Basel)
. 2021 Jan;
13(2).
PMID: 33477882
Next-generation sequencing of primary tumors is now standard for transcriptomic studies, but microarray-based data still constitute the majority of available information on other clinically valuable samples, including archive material. Using...
2.
Mao X, Li J, Xu X, Boyd L, He W, Stankiewicz E, et al.
Am J Cancer Res
. 2014 Dec;
4(6):886-96.
PMID: 25520876
While androgen and androgen receptor (AR) activity have been strongly implicated in prostate cancer development and therapy, the influence of the CAG repeat, which is found within the first exon...
3.
Yeste-Velasco M, Mao X, Grose R, Kudahetti S, Lin D, Marzec J, et al.
J Pathol
. 2014 Jan;
232(5):566-77.
PMID: 24407904
Genomic changes affecting tumour suppressor genes are fundamental to cancer. We applied SNP array analysis to a panel of testicular germ cell tumours to search for novel tumour suppressor genes...
4.
Xue L, Mao X, Ren G, Stankiewicz E, Kudahetti S, Lin D, et al.
Am J Cancer Res
. 2012 Dec;
2(6):736-44.
PMID: 23226619
We have previously reported genetic differences between Western and Chinese prostate cancers, including different frequencies of ERG rearrangements. We investigated further ERG expression and rearrangements in prostate cancers and high-grade...
5.
Boyd L, Mao X, Xue L, Lin D, Chaplin T, Kudahetti S, et al.
Genes Chromosomes Cancer
. 2012 Feb;
51(6):579-89.
PMID: 22334418
Many human cancers present as multifocal lesions. Understanding the clonal origin of multifocal cancers is of both etiological and clinical importance. The molecular basis of multifocal prostate cancer has previously...
6.
Vasiljevic N, Wu K, Brentnall A, Kim D, Thorat M, Kudahetti S, et al.
Dis Markers
. 2011 Jun;
30(4):151-61.
PMID: 21694441
Aberrant DNA methylation plays a pivotal role in carcinogenesis and its mapping is likely to provide biomarkers for improved diagnostic and risk assessment in prostate cancer (PCa). We quantified and...
7.
Bastus N, Boyd L, Mao X, Stankiewicz E, Kudahetti S, Oliver R, et al.
Cancer Res
. 2010 Oct;
70(23):9544-8.
PMID: 20947519
Fusion genes play important roles in tumorigenesis. The identification of the high-frequency TMPRSS2 fusion with ERG and other ETS family genes in prostate cancer highlights the importance of fusion genes...
8.
Kudahetti S, Fisher G, Ambroisine L, Prowse D, Kattan M, Foster C, et al.
Pathology
. 2010 Sep;
42(6):519-23.
PMID: 20854069
Aims: Treatment decisions are difficult in clinically localised prostate cancer and further biomarkers of aggressive behaviour are required. We investigated the hypothesis that the tissue expression of three cell cycle...
9.
Mao X, Yu Y, Boyd L, Ren G, Lin D, Chaplin T, et al.
Cancer Res
. 2010 Jun;
70(13):5207-12.
PMID: 20516122
Prostate cancer is significantly more common in Western men than in Asian men, but the basis for this difference remains unknown. Because genomic studies of Asian prostate cancer are very...
10.
Noel E, Yeste-Velasco M, Mao X, Perry J, Kudahetti S, Li N, et al.
Am J Pathol
. 2010 Apr;
176(6):2607-15.
PMID: 20395447
Development of chemoresistance limits the clinical efficiency of platinum-based therapy. Although many resistance mechanisms have been demonstrated, genetic/molecular alterations responsible for drug resistance in the majority of clinical cases have...