Sajith Nair
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Explore the profile of Sajith Nair including associated specialties, affiliations and a list of published articles.
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10
Citations
167
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Recent Articles
1.
Nair S, Wu Y, Nguyen T, Fink K, Luo D, Ruedl C
Front Immunol
. 2022 Jul;
13:910192.
PMID: 35784329
Viral respiratory infections cause substantial health and economic burden. There is a pressing demand for efficacious vaccination strategies and, therefore, a need for a better understanding of the mechanisms of...
2.
Chen Q, Nair S, Ruedl C
Life Sci Alliance
. 2021 Nov;
5(1).
PMID: 34728557
The gut immune system has evolved to co-exist in a mutually beneficial symbiotic relationship with its microflora. Here, using a germ-free fate-mapping mouse model, we provide clear insight into how...
3.
Nair S, Bist P, Dikshit N, Krishnan M
Sci Rep
. 2016 Oct;
6:36179.
PMID: 27782195
Type I interferon (IFN-I) mediated innate immune response controls virus infections by inducing the expression of interferon stimulated genes (ISGs). Although ubiquitination plays key roles in immune signaling regulation, a...
4.
Pulloor N, Nair S, McCaffrey K, Kostic A, Bist P, Weaver J, et al.
PLoS Pathog
. 2014 Mar;
10(2):e1003981.
PMID: 24586175
The pattern recognition receptor RIG-I is critical for Type-I interferon production. However, the global regulation of RIG-I signaling is only partially understood. Using a human genome-wide RNAi-screen, we identified 226...
5.
Anoop M, Mathew A, Jayakumar B, Issac A, Nair S, Abraham R, et al.
Virus Genes
. 2012 Jun;
45(1):1-13.
PMID: 22729802
In this study, dengue virus (DENV) isolates from a localized, small-scale, non-seasonal dengue outbreak were genetically characterized. The outbreak occurred during the pre-monsoon months (April-May) in a medical college campus...
6.
Nair S, Arathy D, Issac A, Sreekumar E
Virol J
. 2011 Jul;
8:363.
PMID: 21781334
Background: The human hepatitis B virus (HBV), a member of the hepadna viridae, causes acute or chronic hepatitis B, and hepatocellular carcinoma (HCC). The duck hepatitis B virus (DHBV) infection,...
7.
Arathy D, Nair S, Soman S, Issac A, Sreekumar E
Dev Comp Immunol
. 2010 Sep;
35(1):142-50.
PMID: 20850473
RANTES (Regulated upon Activation, Normal T-cell Expressed and Secreted) is a key pro-inflammatory cytokine that belongs to the CC-group of chemokines. The present study was carried out to functionally characterize...
8.
Niyas K, Abraham R, Unnikrishnan R, Mathew T, Nair S, Manakkadan A, et al.
Virol J
. 2010 Aug;
7:189.
PMID: 20704755
Chikungunya virus (CHIKV), an arthritogenic alphavirus, is transmitted to humans by infected Aedes (Ae.) aegypti and Ae.albopictus mosquitoes. In the study, reverse-transcription PCR (RT PCR) and virus isolation detected CHIKV...
9.
Sreekumar E, Issac A, Nair S, Hariharan R, Janki M, Arathy D, et al.
Virus Genes
. 2009 Oct;
40(1):14-27.
PMID: 19851853
Chikungunya virus (CHIKV), a positive-stranded alphavirus, causes epidemic febrile infections characterized by severe and prolonged arthralgia. In the present study, six CHIKV isolates (2006 RGCB03, RGCB05; 2007 RGCB80, RGCB120; 2008...
10.
Soman S, Nair S, Issac A, Arathy D, Niyas K, Anoop M, et al.
Mol Immunol
. 2009 Jul;
46(15):3070-5.
PMID: 19577301
The present study analyzed the immunomodulatory potential of a newly identified duck beta-defensin, Apl_AvBD2. Recombinant Apl_AvBD2 expressed in HEK293T cells induced a concentration dependent in vitro migration of duck splenocytes,...