Saiyong Pan
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Explore the profile of Saiyong Pan including associated specialties, affiliations and a list of published articles.
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8
Citations
26
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Recent Articles
1.
Nicolaou K, Pan S, Shelke Y, Rigol S, Bao R, Das D, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(32):e2208938119.
PMID: 35930662
A unified synthetic route for the total syntheses of eribulin and a macrolactam analog of halichondrin B is described. The key to the success of the current synthetic approach includes...
2.
Nicolaou K, Pan S, Shelke Y, Ye Q, Das D, Rigol S
J Am Chem Soc
. 2021 Dec;
143(49):20970-20979.
PMID: 34851106
A new synthetic strategy for the total synthesis of norhalichondrin B featuring a highly convergent approach and our recently disclosed reverse approach for the synthesis of cyclic ether structural motifs...
3.
Nicolaou K, Pan S, Shelke Y, Das D, Ye Q, Lu Y, et al.
J Am Chem Soc
. 2021 Jun;
143(24):9267-9276.
PMID: 34105959
A new strategy is described for the total synthesis of halichondrin B featuring reversal of the sequential construction of a number of its cyclic ethers from the classical approach by...
4.
Nicolaou K, Pan S, Pulukuri K, Ye Q, Rigol S, Erande R, et al.
J Org Chem
. 2021 Feb;
86(4):3377-3421.
PMID: 33544599
Molecular design, synthesis, and biological evaluation of tubulysin analogues, linker-drugs, and antibody-drug conjugates are described. Among the new discoveries reported is the identification of new potent analogues within the tubulysin...
5.
Pan S, Chen S, Dong G
Angew Chem Int Ed Engl
. 2018 Apr;
57(21):6333-6336.
PMID: 29644802
Divergent total syntheses of the enmein-type natural products (-)-enmein, (-)-isodocarpin, and (-)-sculponin R have been achieved in a concise fashion. Key features of the strategy include 1) an efficient early-stage...
6.
Pan S, Gao B, Hu J, Xuan J, Xie H, Ding H
Chemistry
. 2015 Dec;
22(3):959-70.
PMID: 26660855
The first enantioselective total synthesis of (+)-steenkrotin A has been achieved in 18 steps and 4.2 % overall yield. The key features of the strategy entail a Rh-catalyzed O-H bond...
7.
Pan S, Xuan J, Gao B, Zhu A, Ding H
Angew Chem Int Ed Engl
. 2015 Apr;
54(23):6905-8.
PMID: 25891977
A concise and diastereoselective total synthesis of the diterpenoid (±)-steenkrotin A is described for the first time. The strategy mainly features three key ring formations: 1) a rhodium-catalyzed O-H bond...
8.
Xuan J, Pan S, Zhang Y, Ye B, Ding H
Org Biomol Chem
. 2014 Dec;
13(6):1643-6.
PMID: 25535835
A concise and diastereoselective route to the angularly fused [5-6-7] tricyclic carbon framework of the steenkrotin-type diterpenoids was reported. The key features of the strategy are based on an intramolecular...