Saima Zafar
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Explore the profile of Saima Zafar including associated specialties, affiliations and a list of published articles.
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72
Citations
945
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Recent Articles
1.
Nazir M, Farzeen I, Zafar S, Fatima S, Zafar N, Ashraf A, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2025 Feb;
PMID: 40014130
Chicoric acid (CA), a polyphenolic compound found in chicory (Cichorium intybus), shows potential for the management of a number of diseases due to its antioxidant, anticancer, anti-inflammatory, and insulin-sensitizing properties....
2.
Kucukali F, Hill E, Watzeels T, Hummerich H, Campbell T, Darwent L, et al.
Brain
. 2025 Jan;
PMID: 39865733
Prions are assemblies of misfolded prion protein that cause several fatal and transmissible neurodegenerative diseases, with the most common phenotype in humans being sporadic Creutzfeldt-Jakob disease (sCJD). Aside from variation...
3.
Rasheed U, Khalid M, Noor A, Saeed U, Uppal R, Zafar S
Prion
. 2024 Dec;
18(1):1-7.
PMID: 39654135
Rapidly progressive dementias (RPDs) are a type of fatal dementias that cause rapid progression of neuronal dysfunction. This study aimed to assess the prevalence of APOE genotypes (ε2, ε3, ε4)...
4.
Hummerich H, Speedy H, Campbell T, Darwent L, Hill E, Collins S, et al.
PLoS One
. 2024 Jul;
19(7):e0304528.
PMID: 39079175
Human prion diseases are rare, transmissible and often rapidly progressive dementias. The most common type, sporadic Creutzfeldt-Jakob disease (sCJD), is highly variable in clinical duration and age at onset. Genetic...
5.
Khan M, Riaz H, Jatala F, Noor A, Mumtaz S, Zafar S
Yale J Biol Med
. 2024 Jul;
97(2):141-152.
PMID: 38947105
Nodal regions, areas of intensive contact between Schwann cells and axons, may be exceptionally vulnerable to diabetes-induced changes because they are exposed to and impacted by the metabolic implications of...
6.
Khan S, Jatala F, Muti A, Afza N, Noor A, Mumtaz S, et al.
Yale J Biol Med
. 2024 Jul;
97(2):153-164.
PMID: 38947101
The blood-brain barrier (BBB) prevents the use of many drugs for the treatment of neurological disorders. Recently, nitrogen-doped carbon dots (NCDs) have emerged as promising nanocarriers to cross BBB. The...
7.
Zafar S, Ashraf A, Hayat S, Siddique M, Waseem M, Hassan M, et al.
Environ Monit Assess
. 2024 Apr;
196(5):412.
PMID: 38565815
Cadmium (Cd) is a highly toxic metal that frequently contaminates our environment. In this study, the bioflocculant-producing, cadmium-resistant Escherichia fergusonii ZSF-15 was characterized from Paharang drain, Bawa Chak, Faisalabad, Pakistan....
8.
Rasheed U, Khan S, Khalid M, Noor A, Zafar S
Prion
. 2024 Feb;
18(1):11-27.
PMID: 38323574
Creutzfeldt Jakob Disease (CJD) is a rapidly progressive, fatal neurodegenerative disorder, also known as a subacute spongiform encephalopathy. There are three major subtypes of CJD i.e. Sporadic CJD, which occurs...
9.
Zafar S, Fatima S, Schmitz M, Zerr I
Biomolecules
. 2024 Jan;
14(1).
PMID: 38254718
Neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and Huntington's disease, are identified and characterized by the progressive loss of neurons and neuronal dysfunction, resulting in cognitive and motor impairment....
10.
Younas N, Zafar S, Saleem T, Fernandez Flores L, Younas A, Schmitz M, et al.
Cell Biosci
. 2023 Dec;
13(1):221.
PMID: 38041189
Background: Aberrant stress granules (SGs) are emerging as prime suspects in the nucleation of toxic protein aggregates. Understanding the molecular networks linked with aggregation-prone proteins (prion protein, synuclein, and tau)...