Sailesh Varia
Overview
Explore the profile of Sailesh Varia including associated specialties, affiliations and a list of published articles.
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7
Citations
70
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Recent Articles
1.
Vaidhyanathan S, Wang X, Crison J, Varia S, Gao J, Saxena A, et al.
J Pharm Sci
. 2018 Nov;
108(1):741-749.
PMID: 30439460
SPRYCEL (Dasatinib) is a Biopharmaceutical Classification System II weakly basic drug that exhibits strong pH-dependent solubility. Dasatinib is currently presented in 2 drug product formulations as an adult immediate release...
2.
Narang A, Breckenridge L, Guo H, Wang J, Wolf A, Desai D, et al.
J Pharm Sci
. 2016 Oct;
106(1):200-207.
PMID: 27686683
Surface erosion of uncoated tablets results in processing problems such as dusting and defects during coating and is governed by the strength of particle bonding on tablet surface. In this...
3.
Narang A, Sheverev V, Stepaniuk V, Badawy S, Stevens T, Macias K, et al.
J Pharm Sci
. 2014 Dec;
104(3):1019-34.
PMID: 25470221
Real-time monitoring and control of high shear wet granulation (HSWG) using process analytical technologies is crucial to process design, scale-up, and reproducible manufacture. Although significant progress has been made in...
4.
Narang A, Yamniuk A, Zhang L, Comezoglu S, Bindra D, Varia S, et al.
J Pharm Pharmacol
. 2012 Mar;
64(4):553-65.
PMID: 22420661
Objectives: Drug-excipient binding can affect in-vitro drug release. Literature suggests that drug-excipient ionic binding interaction that is not disrupted by physiological salt concentration in the dissolution medium can impact a...
5.
Wang J, Hemenway J, Chen W, Desai D, Early W, Paruchuri S, et al.
Int J Pharm
. 2012 Feb;
427(2):163-9.
PMID: 22301427
Effects of material and manufacturing process parameters on the efficiency of an aqueous active tablet film-coating process in a perforated pan coater were evaluated. Twenty-four batches representing various core tablet...
6.
Narang A, Varia S
Adv Drug Deliv Rev
. 2011 Apr;
63(8):640-58.
PMID: 21514334
Tumor targeted drug delivery has the potential to improve cancer care by reducing non-target toxicities and increasing the efficacy of a drug. Tumor targeted delivery of a drug from the...
7.
Ueda Y, Matiskella J, Golik J, Connolly T, Hudyma T, Venkatesh S, et al.
Bioorg Med Chem Lett
. 2003 Oct;
13(21):3669-72.
PMID: 14552754
Synthesis of phosphonooxymethyl derivatives of ravuconazole, 2 (BMS-379224) and 3 (BMS-315801) and their biological evaluation as potential water-soluble prodrugs of ravuconazole are described. The phosphonooxymethyl ether analogue 2 (BMS-379224) and...