Saedis Saevarsdottir
Overview
Explore the profile of Saedis Saevarsdottir including associated specialties, affiliations and a list of published articles.
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105
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2292
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Recent Articles
1.
Glintborg B, Hansson M, Hammer H, Klareskog L, Saevarsdottir S, Westerlind H, et al.
Scand J Public Health
. 2024 Dec;
52(8):1019-1025.
PMID: 39651649
Aims: Personalised medicine in chronic complex diseases such as rheumatoid arthritis (RA) is within reach but requires international multi-stakeholder collaboration. We exemplify how national implementations of the General Data Protection...
2.
Ivarsdottir E, Gudmundsson J, Tragante V, Sveinbjornsson G, Kristmundsdottir S, Stacey S, et al.
Nat Genet
. 2024 Oct;
56(11):2422-2433.
PMID: 39472694
Discovery of cancer risk variants in the sequence of the germline genome can shed light on carcinogenesis. Here we describe gene burden association analyses, aggregating rare missense and loss of...
3.
Kristjansdottir K, Norddahl G, Ivarsdottir E, Halldorsson G, Einarsson G, Bjarnadottir K, et al.
J Allergy Clin Immunol
. 2024 Oct;
155(1):228-235.
PMID: 39423878
Background: Signal transducer and activator of transcription 6 (STAT6) is central to type 2 (T2) inflammation, and common noncoding variants at the STAT6 locus associate with various T2 inflammatory traits,...
4.
Olafsdottir T, Thorleifsson G, Lopez de Lapuente Portilla A, Jonsson S, Stefansdottir L, Niroula A, et al.
Nat Commun
. 2024 Sep;
15(1):8054.
PMID: 39277589
Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy...
5.
Aegisdottir H, Andreasen L, Thorolfsdottir R, Sveinbjornsson G, Jonsdottir A, Stefansdottir L, et al.
JAMA Cardiol
. 2024 Sep;
9(11):1053-1058.
PMID: 39230897
Importance: Understanding of the genetics of accessory atrioventricular pathways (APs) and affiliated arrhythmias is limited. Objective: To investigate the genetics of APs and affiliated arrhythmias. Design, Setting, And Participants: This...
6.
Stefansson O, Sigurpalsdottir B, Rognvaldsson S, Halldorsson G, Juliusson K, Sveinbjornsson G, et al.
Nat Genet
. 2024 Jul;
56(8):1624-1631.
PMID: 39048797
Gene promoter and enhancer sequences are bound by transcription factors and are depleted of methylated CpG sites (cytosines preceding guanines in DNA). The absence of methylated CpGs in these sequences...
7.
Saevarsdottir S, Bjarnadottir K, Markusson T, Berglund J, Olafsdottir T, Halldorsson G, et al.
Nat Commun
. 2024 Jul;
15(1):5748.
PMID: 38982041
Autoimmune thyroid disease (AITD) is a common autoimmune disease. In a GWAS meta-analysis of 110,945 cases and 1,084,290 controls, 290 sequence variants at 225 loci are associated with AITD. Of...
8.
Sysojev A, Alfredsson L, Klareskog L, Silberberg G, Saevarsdottir S, Padyukov L, et al.
Arthritis Rheumatol
. 2024 May;
76(9):1344-1352.
PMID: 38782598
Objective: The aim of this study was to investigate whether a shared genetic susceptibility exists between individuals with rheumatoid arthritis (RA) and individuals with myocardial infarction (MI)-including major MI risk...
9.
Hjorleifsson Eldjarn G, Ferkingstad E, Lund S, Helgason H, Magnusson O, Gunnarsdottir K, et al.
Nature
. 2024 May;
630(8015):E3.
PMID: 38778117
No abstract available.
10.
Takase-Minegishi K, Bohringer S, Nam J, Kaneko Y, Behrens F, Saevarsdottir S, et al.
Rheumatology (Oxford)
. 2024 Feb;
64(2):548-560.
PMID: 38366945
Objective: To investigate the efficacy of bDMARDs in patients with RA with RF/ACPA compared with patients without these autoantibodies. Methods: Previous systematic literature reviews performed by EULAR RA management task...