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Sade M Spencer

Explore the profile of Sade M Spencer including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 103
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Recent Articles
1.
Grigsby K, Palacios J, Chan A, Spencer S, Ozburn A
Alcohol Clin Exp Res (Hoboken) . 2024 Nov; 48(12):2269-2280. PMID: 39589266
Background: Adenosine monophosphate-activated protein kinase (AMPK) signaling plays a vital role in regulating cellular metabolism and energy throughout the body. Ethanol and cocaine both reduce AMPK activity in addiction-related brain...
2.
Brewer A, Felter C, Sternitzky A, Spencer S
Pharmacol Biochem Behav . 2024 Jan; 236:173707. PMID: 38244864
Synthetic cannabinoids are associated with higher risk of dependence and more intense withdrawal symptoms than plant-derived Δ9-tetrahydrocannabinol (THC). Avoidance of withdrawal symptoms, including anxiogenic effects, can contribute to continued cannabinoid...
3.
Ozburn A, Spencer S
Neuropsychopharmacology . 2023 Aug; 49(1):317-318. PMID: 37550437
No abstract available.
4.
Chan A, Willard A, Mulloy S, Ibrahim N, Sciaccotta A, Schonfeld M, et al.
Addict Biol . 2022 Apr; 27(3):e13165. PMID: 35470560
This study investigated the potential therapeutic effects of the FDA-approved drug metformin on cue-induced reinstatement of cocaine seeking. Metformin (dimethyl-biguanide) is a first-line treatment for type II diabetes that, among...
5.
Turk M, Bakker C, Spencer S, Lofgren S
Psychoneuroendocrinology . 2022 Jan; 138:105665. PMID: 35063687
Background: Major depressive disorder is the most common neuropsychiatric comorbidity of human immunodeficiency virus (HIV), and women are more frequently affected in the general population and among those with HIV....
6.
Neuhofer D, Spencer S, Chioma V, Beloate L, Schwartz D, Kalivas P
Addict Biol . 2019 Nov; 25(6):e12843. PMID: 31733097
Glutamatergic plasticity in the nucleus accumbens core (NAcore) is a key neuronal process in appetitive learning and contributes to pathologies such as drug addiction. Understanding how this plasticity factors into...
7.
Namba M, Kupchik Y, Spencer S, Garcia-Keller C, Goenaga J, Powell G, et al.
Addict Biol . 2019 Jul; 25(5):e12797. PMID: 31330570
Nicotine self-administration is associated with decreased expression of the glial glutamate transporter (GLT-1) and the cystine-glutamate exchange protein xCT within the nucleus accumbens core (NAcore). N-acetylcysteine (NAC) has been shown...
8.
Roberts-Wolfe D, Heinsbroek J, Spencer S, Bobadilla A, Smith A, Gipson C, et al.
Addict Biol . 2019 May; 25(3):e12759. PMID: 31062493
Repeated exposure to drug-associated cues without reward (extinction) leads to refraining from drug seeking in rodents. We determined if refraining is associated with transient synaptic plasticity (t-SP) in nucleus accumbens...
9.
Ozburn A, Falcon E, Twaddle A, Nugent A, Gillman A, Spencer S, et al.
Biol Psychiatry . 2014 Dec; 77(5):425-433. PMID: 25444159
Background: Circadian gene disruptions are associated with the development of psychiatric disorders, including addiction. However, the mechanisms by which circadian genes regulate reward remain poorly understood. Methods: We used mice...