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Sabrina L Mitchell

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Articles 18
Citations 334
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Recent Articles
1.
Breeyear J, Mitchell S, Nealon C, Hellwege J, Charest B, Khakharia A, et al.
J Am Med Inform Assoc . 2024 Aug; 31(11):2560-2570. PMID: 39158361
Objectives: To develop, validate, and implement algorithms to identify diabetic retinopathy (DR) cases and controls from electronic health care records (EHRs). Materials And Methods: We developed and validated electronic health...
2.
Breeyear J, Hellwege J, Schroeder P, House J, Poisner H, Mitchell S, et al.
Nat Med . 2024 Jun; 30(9):2480-2488. PMID: 38918629
Diabetes complications occur at higher rates in individuals of African ancestry. Glucose-6-phosphate dehydrogenase deficiency (G6PDdef), common in some African populations, confers malaria resistance, and reduces hemoglobin A1c (HbA1c) levels by...
3.
Breeyear J, Mitchell S, Nealon C, Hellwege J, Charest B, Khakharia A, et al.
medRxiv . 2023 Nov; PMID: 38014167
Objectives: To develop, validate and implement algorithms to identify diabetic retinopathy (DR) cases and controls from electronic health care records (EHR)s. : We developed and validated EHR-based algorithms to identify...
4.
Mitchell S, Ma C, Scott W, Agarwal A, Pericak-Vance M, Haines J, et al.
Cells . 2021 Nov; 10(11). PMID: 34831363
To characterize metabolites and metabolic pathways altered in intermediate and neovascular age-related macular degeneration (IAMD and NVAMD), high resolution untargeted metabolomics was performed via liquid chromatography-mass spectrometry on plasma samples...
5.
Peters K, Rivera E, Warden C, Harlow P, Mitchell S, Calcutt M, et al.
Am J Ophthalmol . 2021 Sep; 235:154-162. PMID: 34587493
Purpose: To determine if plasma levels of six arginine-related and citrulline-related metabolites (arginine, citrulline, asymmetric dimethylarginine [ADMA], ornithine, proline, and argininosuccinate) differ between patients with type 2 diabetes and diabetic...
6.
Mitchell S, Leon D, Chaugai S, Kawai V, Levinson R, Wei W, et al.
Pharmacogenomics J . 2020 Jun; 20(6):831-839. PMID: 32504053
Hypoglycemia is a common complication among type 2 diabetes mellitus (T2DM) patients receiving sulfonylurea therapy. The aim of this study was to determine if genetic contributions to sulfonylurea pharmacokinetics or...
7.
Sumarriva K, Uppal K, Ma C, Herren D, Wang Y, Chocron I, et al.
Invest Ophthalmol Vis Sci . 2019 Jul; 60(8):3119-3126. PMID: 31323682
Purpose: To determine plasma metabolite and metabolic pathway differences between patients with type 2 diabetes with diabetic retinopathy (DR) and without retinopathy (diabetic controls), and between patients with proliferative DR...
8.
Mitchell S, Uppal K, Williamson S, Liu K, Burgess L, Tran V, et al.
Invest Ophthalmol Vis Sci . 2018 Oct; 59(12):4978-4985. PMID: 30326066
Purpose: To identify metabolites and metabolic pathways altered in neovascular age-related macular degeneration (NVAMD). Methods: We performed metabolomics analysis using high-resolution C18 liquid chromatography-mass spectrometry on plasma samples from 100...
9.
Smieszek S, Mitchell S, Farber-Eger E, Veatch O, Wheeler N, Goodloe R, et al.
PeerJ . 2018 Jul; 6:e5149. PMID: 29967758
Effective approaches for assessing mitochondrial DNA (mtDNA) variation are important to multiple scientific disciplines. Mitochondrial haplogroups characterize branch points in the phylogeny of mtDNA. Several tools exist for mitochondrial haplogroup...
10.
Mitchell S, Neininger A, Bruce C, Chocron I, Bregman J, Estopinal C, et al.
Invest Ophthalmol Vis Sci . 2017 Dec; 58(14):6481-6488. PMID: 29288266
Purpose: We previously demonstrated an association between European mitochondrial haplogroups and proliferative diabetic retinopathy (PDR). The purpose of this study was to determine how the relationship between these haplogroups and...