Karan Uppal
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Explore the profile of Karan Uppal including associated specialties, affiliations and a list of published articles.
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111
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3131
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Recent Articles
1.
He D, Yan Q, Uppal K, Walker D, Jones D, Ritz B, et al.
Metabolomics
. 2025 Feb;
21(2):30.
PMID: 39979646
Introduction: Maternal tobacco smoking in the perinatal period increases the risk for adverse outcomes in offspring. Objective: To better understand the biological pathways through which maternal tobacco use may have...
2.
Islam S, Liu C, Mohandas A, Rooney K, Nayak A, Mehta A, et al.
Sci Rep
. 2024 Jan;
14(1):1794.
PMID: 38245568
Plasma metabolomics profiling is an emerging methodology to identify metabolic pathways underlying cardiovascular health (CVH). The objective of this study was to define metabolomic profiles underlying CVH in a cohort...
3.
Yan Q, He D, Walker D, Uppal K, Wang X, Orimoloye H, et al.
EJC Paediatr Oncol
. 2023 Dec;
2.
PMID: 38130370
Background: Retinoblastoma is rare but nevertheless the most common pediatric eye cancer that occurs in children under age 5. High-resolution metabolomics (HRM) is a powerful analytical approach to profile metabolic...
4.
He D, Yan Q, Uppal K, Walker D, Jones D, Ritz B, et al.
Am J Epidemiol
. 2023 May;
192(10):1720-1730.
PMID: 37218607
Epidemiologic studies of low-frequency exposures or outcomes using metabolomics analyses of neonatal dried blood spots (DBS) often require assembly of samples with substantial differences in duration of storage. Independent assessment...
5.
Fernandes J, Uppal K, Liu K, Hu X, Orr M, Tran V, et al.
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107179
Antagonistic interaction refers to opposing beneficial and adverse signaling by a single agent. Understanding opposing signaling is important because pathologic outcomes can result from adverse causative agents or the failure...
6.
He D, Huang X, Uppal K, Coleman A, Walker D, Ritz B, et al.
Retina
. 2023 Feb;
43(3):481-489.
PMID: 36730579
Purpose: Previous studies examining the risk of retinoblastoma with maternal smoking were inconclusive, likely due in part to the reliance on self-reported maternal smoking. This study uses biomarkers of tobacco...
7.
DeBarry J, Nural M, Pakala S, Nayak V, Warrenfeltz S, Humphrey J, et al.
Sci Data
. 2022 Nov;
9(1):722.
PMID: 36433985
Plasmodium cynomolgi causes zoonotic malarial infections in Southeast Asia and this parasite species is important as a model for Plasmodium vivax and Plasmodium ovale. Each of these species produces hypnozoites...
8.
Zuniga L, Lessmann T, Uppal K, Bisek N, Hong E, Rasmussen C, et al.
Cancer Cell Int
. 2022 Sep;
22(1):286.
PMID: 36123697
Background: Intratumoral (IT) delivery of toll-like receptor (TLR) agonists has shown encouraging anti-tumor benefit in preclinical and early clinical studies. However, IT delivery of TLR agonists may lead to rapid...
9.
Rosen D, Kvarnhammar A, Laufer B, Knappe T, Karlsson J, Hong E, et al.
J Immunother Cancer
. 2022 Jul;
10(7).
PMID: 35817480
Background: Recombinant interleukin-2 (IL-2, aldesleukin) is an approved cancer immunotherapy but causes severe toxicities including cytokine storm and vascular leak syndrome (VLS). IL-2 promotes antitumor function of IL-2Rβ/γ natural killer...
10.
Tso J, Liu C, Turner C, Uppal K, Prabakaran G, Ejaz K, et al.
Med Sci Sports Exerc
. 2022 May;
54(10):1617-1624.
PMID: 35617604
Purpose: Metabolomics identifies molecular products produced in response to numerous stimuli, including both adaptive (includes exercise training) and disease processes. We analyzed a longitudinal cohort of American-style football (ASF) athletes,...