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Sabarinadh Chilaka

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Articles 9
Citations 298
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Recent Articles
1.
Walvekar K, Tirunavalli S, Eedara A, Chandra Y, Kuncha M, B R Kumar A, et al.
Inflammation . 2024 Jul; PMID: 39017810
Psoriasis is a chronic skin inflammatory disorder characterized by the hyper-activation of the immune system and the over-proliferation of epidermal keratinocytes. This study aimed to investigate the anti-psoriatic activity of...
2.
Tirunavalli S, Pramatha S, Eedara A, Walvekar K, Immanuel C, Potdar P, et al.
Life Sci . 2023 Aug; 330:122027. PMID: 37597767
Aims: Acute lung inflammation, particularly acute respiratory distress syndrome (ARDS), is caused by a variety of pathogens including bacteria and viruses. β-Glucans have been reported to possess both anti-inflammatory and...
3.
Jaffery H, Huesa C, Chilaka S, Cole J, Doonan J, Akbar M, et al.
Arthritis Rheumatol . 2023 Jul; 75(12):2148-2160. PMID: 37410754
Objective: IĸB protein B cell lymphoma 3-encoded protein (BCL3) is a regulator of the NF-κB family of transcription factors. NF-κB signaling fundamentally influences the fate of bone-forming osteoblasts and bone-resorbing...
4.
Ansalone C, Cole J, Chilaka S, Sunzini F, Sood S, Robertson J, et al.
Ann Rheum Dis . 2021 Mar; 80(6):748-757. PMID: 33692019
Objectives: Circulating myeloid precursors are responsible for post-natal osteoclast (OC) differentiation and skeletal health, although the exact human precursors have not been defined. Enhanced osteoclastogenesis contributes to joint destruction in...
5.
Brossas C, Valton A, Venev S, Chilaka S, Counillon A, Laurent M, et al.
EMBO J . 2020 Sep; 39(21):e99520. PMID: 32935369
Vertebrate genomes replicate according to a precise temporal program strongly correlated with their organization into A/B compartments. Until now, the molecular mechanisms underlying the establishment of early-replicating domains remain largely...
6.
Akbar M, Garcia-Melchor E, Chilaka S, Little K, Sood S, Reilly J, et al.
Sci Adv . 2020 Jul; 6(28):eaaz8272. PMID: 32695877
Fibrotic disorders represent common complex disease pathologies that are therapeutically challenging. Inflammation is associated with numerous fibrotic pathogeneses; however, its role in the multifaceted mechanisms of fibrosis remains unclear. IL-13...
7.
Alivernini S, MacDonald L, Elmesmari A, Finlay S, Tolusso B, Gigante M, et al.
Nat Med . 2020 Jul; 26(8):1295-1306. PMID: 32601335
Immune-regulatory mechanisms of drug-free remission in rheumatoid arthritis (RA) are unknown. We hypothesized that synovial tissue macrophages (STM), which persist in remission, contribute to joint homeostasis. We used single-cell transcriptomics...
8.
Duriez B, Chilaka S, Bercher J, Hercul E, Prioleau M
Nucleic Acids Res . 2019 Mar; 47(10):5155-5169. PMID: 30926993
Eukaryotic genomes are replicated under the control of a highly sophisticated program during the restricted time period corresponding to S phase. The most widely used replication timing assays, which are...
9.
Hassan-Zadeh V, Chilaka S, Cadoret J, Ma M, Boggetto N, West A, et al.
PLoS Biol . 2012 Mar; 10(3):e1001277. PMID: 22412349
The nuclear genomes of vertebrates show a highly organized program of DNA replication where GC-rich isochores are replicated early in S-phase, while AT-rich isochores are late replicating. GC-rich regions are...